Zininga T - Search Results

1

Extracts Obtained from Pterocarpus angolensis DC and Ziziphus mucronata Exhibit Antiplasmodial Activity and Inhibit Heat Shock Protein 70 (Hsp70) Function.

Zininga T, Anokwuru CP, Sigidi MT, Tshisikhawe MP, Ramaite IID, Traoré AN, Hoppe H, Shonhai A, Potgieter N. Zininga T, et al. Molecules. 2017 Jul 28;22(8):1224. doi: 10.3390/molecules22081224. Molecules. 2017. PMID: 28788073 Free PMC article.

2

Overexpression, Purification and Characterisation of the Plasmodium falciparum Hsp70-z (PfHsp70-z) Protein.

Zininga T, Achilonu I, Hoppe H, Prinsloo E, Dirr HW, Shonhai A. Zininga T, et al. PLoS One. 2015 Jun 17;10(6):e0129445. doi: 10.1371/journal.pone.0129445. eCollection 2015. PLoS One. 2015. PMID: 26083397 Free PMC article.

3

Plasmodium falciparum Hop (PfHop) Interacts with the Hsp70 Chaperone in a Nucleotide-Dependent Fashion and Exhibits Ligand Selectivity.

Zininga T, Makumire S, Gitau GW, Njunge JM, Pooe OJ, Klimek H, Scheurr R, Raifer H, Prinsloo E, Przyborski JM, Hoppe H, Shonhai A. Zininga T, et al. PLoS One. 2015 Aug 12;10(8):e0135326. doi: 10.1371/journal.pone.0135326. eCollection 2015. PLoS One. 2015. PMID: 26267894 Free PMC article.

4

Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion.

Zininga T, Achilonu I, Hoppe H, Prinsloo E, Dirr HW, Shonhai A. Zininga T, et al. Cell Stress Chaperones. 2016 May;21(3):499-513. doi: 10.1007/s12192-016-0678-4. Epub 2016 Feb 19. Cell Stress Chaperones. 2016. PMID: 26894764 Free PMC article.

5

Use of a Chimeric Hsp70 to Enhance the Quality of Recombinant Plasmodium falciparum S-Adenosylmethionine Decarboxylase Protein Produced in Escherichia coli.

Makhoba XH, Burger A, Coertzen D, Zininga T, Birkholtz LM, Shonhai A. Makhoba XH, et al. Among authors: zininga t. PLoS One. 2016 Mar 31;11(3):e0152626. doi: 10.1371/journal.pone.0152626. eCollection 2016. PLoS One. 2016. PMID: 27031344 Free PMC article.

6

Polymyxin B inhibits the chaperone activity of Plasmodium falciparum Hsp70.

Zininga T, Pooe OJ, Makhado PB, Ramatsui L, Prinsloo E, Achilonu I, Dirr H, Shonhai A. Zininga T, et al. Cell Stress Chaperones. 2017 Sep;22(5):707-715. doi: 10.1007/s12192-017-0797-6. Epub 2017 Apr 28. Cell Stress Chaperones. 2017. PMID: 28455613 Free PMC article.

7

(-)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners.

Zininga T, Ramatsui L, Makhado PB, Makumire S, Achilinou I, Hoppe H, Dirr H, Shonhai A. Zininga T, et al. Molecules. 2017 Dec 5;22(12):2139. doi: 10.3390/molecules22122139. Molecules. 2017. PMID: 29206141 Free PMC article.

8

Structural and biochemical characterization of Plasmodium falciparum Hsp70-x reveals functional versatility of its C-terminal EEVN motif.

Mabate B, Zininga T, Ramatsui L, Makumire S, Achilonu I, Dirr HW, Shonhai A. Mabate B, et al. Among authors: zininga t. Proteins. 2018 Nov;86(11):1189-1201. doi: 10.1002/prot.25600. Epub 2018 Sep 29. Proteins. 2018. PMID: 30183110 Free PMC article.

9

Heat Shock Proteins as Immunomodulants.

Zininga T, Ramatsui L, Shonhai A. Zininga T, et al. Molecules. 2018 Nov 1;23(11):2846. doi: 10.3390/molecules23112846. Molecules. 2018. PMID: 30388847 Free PMC article. Review.

10

Comparative structure-function features of Hsp70s of Plasmodium falciparum and human origins.

Chakafana G, Zininga T, Shonhai A. Chakafana G, et al. Among authors: zininga t. Biophys Rev. 2019 Jul 6;11(4):591-602. doi: 10.1007/s12551-019-00563-w. Online ahead of print. Biophys Rev. 2019. PMID: 31280465 Free PMC article. Review.

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