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Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.
Grajchen E, Loix M, Baeten P, Côrte-Real BF, Hamad I, Vanherle S, Haidar M, Dehairs J, Broos JY, Ntambi JM, Zimmermann R, Breinbauer R, Stinissen P, Hellings N, Verberk SGS, Kooij G, Giera M, Swinnen JV, Broux B, Kleinewietfeld M, Hendriks JJA, Bogie JFJ. Grajchen E, et al. Among authors: zimmermann r. Cell Mol Immunol. 2023 Jun;20(6):666-679. doi: 10.1038/s41423-023-01011-2. Epub 2023 Apr 12. Cell Mol Immunol. 2023. PMID: 37041314 Free PMC article.
Development of small-molecule inhibitors targeting adipose triglyceride lipase.
Mayer N, Schweiger M, Romauch M, Grabner GF, Eichmann TO, Fuchs E, Ivkovic J, Heier C, Mrak I, Lass A, Höfler G, Fledelius C, Zechner R, Zimmermann R, Breinbauer R. Mayer N, et al. Among authors: zimmermann r. Nat Chem Biol. 2013 Dec;9(12):785-7. doi: 10.1038/nchembio.1359. Epub 2013 Oct 6. Nat Chem Biol. 2013. PMID: 24096302 Free PMC article.
Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells.
Taschler U, Schreiber R, Chitraju C, Grabner GF, Romauch M, Wolinski H, Haemmerle G, Breinbauer R, Zechner R, Lass A, Zimmermann R. Taschler U, et al. Among authors: zimmermann r. Biochim Biophys Acta. 2015 Jul;1851(7):937-45. doi: 10.1016/j.bbalip.2015.02.017. Epub 2015 Feb 27. Biochim Biophys Acta. 2015. PMID: 25732851 Free PMC article.
Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling.
Hofer P, Boeszoermenyi A, Jaeger D, Feiler U, Arthanari H, Mayer N, Zehender F, Rechberger G, Oberer M, Zimmermann R, Lass A, Haemmerle G, Breinbauer R, Zechner R, Preiss-Landl K. Hofer P, et al. Among authors: zimmermann r. J Biol Chem. 2015 Jul 24;290(30):18438-53. doi: 10.1074/jbc.M114.628958. Epub 2015 May 7. J Biol Chem. 2015. PMID: 25953897 Free PMC article.
Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Schweiger M, Romauch M, Schreiber R, Grabner GF, Hütter S, Kotzbeck P, Benedikt P, Eichmann TO, Yamada S, Knittelfelder O, Diwoky C, Doler C, Mayer N, De Cecco W, Breinbauer R, Zimmermann R, Zechner R. Schweiger M, et al. Among authors: zimmermann r. Nat Commun. 2017 Mar 22;8:14859. doi: 10.1038/ncomms14859. Nat Commun. 2017. PMID: 28327588 Free PMC article.
Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes.
Grabner GF, Guttenberger N, Mayer N, Migglautsch-Sulzer AK, Lembacher-Fadum C, Fawzy N, Bulfon D, Hofer P, Züllig T, Hartig L, Kulminskaya N, Chalhoub G, Schratter M, Radner FPW, Preiss-Landl K, Masser S, Lass A, Zechner R, Gruber K, Oberer M, Breinbauer R, Zimmermann R. Grabner GF, et al. Among authors: zimmermann r. J Am Chem Soc. 2022 Apr 13;144(14):6237-6250. doi: 10.1021/jacs.1c10836. Epub 2022 Apr 1. J Am Chem Soc. 2022. PMID: 35362954 Free PMC article.
2,056 results