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Generation of a genetically modified pig model with CREBRFR457Q variant.
Li Y, Wang H, Chen H, Liao Y, Gou S, Yan Q, Zhuang Z, Li H, Wang J, Suo Y, Lan T, Liu Y, Zhao Y, Zou Q, Nie T, Hui X, Lai L, Wu D, Fan N. Li Y, et al. Among authors: zhuang z. FASEB J. 2022 Nov;36(11):e22611. doi: 10.1096/fj.202201117. FASEB J. 2022. PMID: 36250915
Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses.
Li W, Shi L, Zhuang Z, Wu H, Lian M, Chen Y, Li L, Ge W, Jin Q, Zhang Q, Zhao Y, Liu Z, Ouyang Z, Ye Y, Li Y, Wang H, Liao Y, Quan L, Xiao L, Lai L, Meng G, Wang K. Li W, et al. Among authors: zhuang z. J Immunol. 2020 Nov 1;205(9):2532-2544. doi: 10.4049/jimmunol.1901468. Epub 2020 Sep 21. J Immunol. 2020. PMID: 32958688
CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.
Li N, Gou S, Wang J, Zhang Q, Huang X, Xie J, Li L, Jin Q, Ouyang Z, Chen F, Ge W, Shi H, Liang Y, Zhuang Z, Zhao X, Lian M, Ye Y, Quan L, Wu H, Lai L, Wang K. Li N, et al. Among authors: zhuang z. Mol Ther. 2021 Mar 3;29(3):1001-1015. doi: 10.1016/j.ymthe.2020.11.023. Epub 2020 Nov 20. Mol Ther. 2021. PMID: 33221434 Free PMC article.
Correction: Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses.
Li W, Shi L, Zhuang Z, Wu H, Lian M, Chen Y, Li L, Ge W, Jin Q, Zhang Q, Zhao Y, Liu Z, Ouyang Z, Ye Y, Li Y, Wang H, Liao Y, Quan L, Xiao L, Lai L, Meng G, Wang K. Li W, et al. Among authors: zhuang z. J Immunol. 2021 Nov 1;207(9):2385-2386. doi: 10.4049/jimmunol.2100753. Epub 2021 Sep 27. J Immunol. 2021. PMID: 34580110 No abstract available.
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.
Liang Y, Xie J, Zhang Q, Wang X, Gou S, Lin L, Chen T, Ge W, Zhuang Z, Lian M, Chen F, Li N, Ouyang Z, Lai C, Liu X, Li L, Ye Y, Wu H, Wang K, Lai L. Liang Y, et al. Among authors: zhuang z. Nucleic Acids Res. 2022 May 20;50(9):5384-5399. doi: 10.1093/nar/gkac353. Nucleic Acids Res. 2022. PMID: 35544322 Free PMC article.
Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression.
Jin Q, Yang X, Gou S, Liu X, Zhuang Z, Liang Y, Shi H, Huang J, Wu H, Zhao Y, Ouyang Z, Zhang Q, Liu Z, Chen F, Ge W, Xie J, Li N, Lai C, Zhao X, Wang J, Lian M, Li L, Quan L, Ye Y, Lai L, Wang K. Jin Q, et al. Among authors: zhuang z. Sci China Life Sci. 2022 Nov;65(11):2269-2286. doi: 10.1007/s11427-021-2088-1. Epub 2022 May 18. Sci China Life Sci. 2022. PMID: 35596888
Generation of pigs with humanized type II collagen by precise human COL2A1 gene knock-in.
Lan T, Zheng Y, Suo Y, Wei Y, Shi H, Yan Q, Zhuang Z, Chen H, Zhang Q, Fan N, Zhao Y, Ouyang Z, Lai C, Liu Z, Zhou J, Tang C, Kim NH, Zou Q, Wang X. Lan T, et al. Among authors: zhuang z. J Genet Genomics. 2023 Mar;50(3):212-215. doi: 10.1016/j.jgg.2022.05.001. Epub 2022 May 20. J Genet Genomics. 2023. PMID: 35598861 No abstract available.
2,757 results