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Inhibition of CYP 17, a new strategy for the treatment of prostate cancer.
Hartmann RW, Ehmer PB, Haidar S, Hector M, Jose J, Klein CD, Seidel SB, Sergejew TF, Wachall BG, Wächter GA, Zhuang Y. Hartmann RW, et al. Among authors: zhuang y. Arch Pharm (Weinheim). 2002 Apr;335(4):119-28. doi: 10.1002/1521-4184(200204)335:4<119::AID-ARDP119>3.0.CO;2-#. Arch Pharm (Weinheim). 2002. PMID: 12112031 Review.
Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge.
Hu Q, Negri M, Jahn-Hoffmann K, Zhuang Y, Olgen S, Bartels M, Müller-Vieira U, Lauterbach T, Hartmann RW. Hu Q, et al. Among authors: zhuang y. Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. doi: 10.1016/j.bmc.2008.07.011. Epub 2008 Jul 9. Bioorg Med Chem. 2008. PMID: 18674917
3,861 results