Zhu Z - Search Results

1

Cancer-associated fibroblast-secreted glucosamine alters the androgen biosynthesis program in prostate cancer via HSD3B1 upregulation.

Cui D, Li J, Zhu Z, Berk M, Hardaway A, McManus J, Chung YM, Alyamani M, Valle S, Tiwari R, Han B, Goudarzi M, Willard B, Sharifi N. Cui D, et al. Among authors: zhu z. J Clin Invest. 2023 Apr 3;133(7):e161913. doi: 10.1172/JCI161913. J Clin Invest. 2023. PMID: 37009898 Free PMC article.

2

DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.

Goodwin JF, Kothari V, Drake JM, Zhao S, Dylgjeri E, Dean JL, Schiewer MJ, McNair C, Jones JK, Aytes A, Magee MS, Snook AE, Zhu Z, Den RB, Birbe RC, Gomella LG, Graham NA, Vashisht AA, Wohlschlegel JA, Graeber TG, Karnes RJ, Takhar M, Davicioni E, Tomlins SA, Abate-Shen C, Sharifi N, Witte ON, Feng FY, Knudsen KE. Goodwin JF, et al. Among authors: zhu z. Cancer Cell. 2015 Jul 13;28(1):97-113. doi: 10.1016/j.ccell.2015.06.004. Cancer Cell. 2015. PMID: 26175416 Free PMC article.

3

Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer.

Li J, Alyamani M, Zhang A, Chang KH, Berk M, Li Z, Zhu Z, Petro M, Magi-Galluzzi C, Taplin ME, Garcia JA, Courtney K, Klein EA, Sharifi N. Li J, et al. Among authors: zhu z. Elife. 2017 Feb 13;6:e20183. doi: 10.7554/eLife.20183. Elife. 2017. PMID: 28191869 Free PMC article.

4

Direct Metabolic Interrogation of Dihydrotestosterone Biosynthesis from Adrenal Precursors in Primary Prostatectomy Tissues.

Dai C, Chung YM, Kovac E, Zhu Z, Li J, Magi-Galluzzi C, Stephenson AJ, Klein EA, Sharifi N. Dai C, et al. Among authors: zhu z. Clin Cancer Res. 2017 Oct 15;23(20):6351-6362. doi: 10.1158/1078-0432.CCR-17-1313. Epub 2017 Jul 21. Clin Cancer Res. 2017. PMID: 28733443 Free PMC article.

5

Functional Silencing of HSD17B2 in Prostate Cancer Promotes Disease Progression.

Gao X, Dai C, Huang S, Tang J, Chen G, Li J, Zhu Z, Zhu X, Zhou S, Gao Y, Hou Z, Fang Z, Xu C, Wang J, Wu D, Sharifi N, Li Z. Gao X, et al. Among authors: zhu x, zhu z. Clin Cancer Res. 2019 Feb 15;25(4):1291-1301. doi: 10.1158/1078-0432.CCR-18-2392. Epub 2018 Sep 18. Clin Cancer Res. 2019. PMID: 30228209 Free PMC article.

6

Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging.

Zhu Z, Chung YM, Sergeeva O, Kepe V, Berk M, Li J, Ko HK, Li Z, Petro M, DiFilippo FP, Lee Z, Sharifi N. Zhu Z, et al. J Biol Chem. 2018 Nov 16;293(46):17829-17837. doi: 10.1074/jbc.RA118.004846. Epub 2018 Sep 27. J Biol Chem. 2018. PMID: 30262668 Free PMC article.

7

Hexose-6-phosphate dehydrogenase blockade reverses prostate cancer drug resistance in xenograft models by glucocorticoid inactivation.

Li J, Berk M, Alyamani M, Sabharwal N, Goins C, Alvarado J, Baratchian M, Zhu Z, Stauffer S, Klein EA, Sharifi N. Li J, et al. Among authors: zhu z. Sci Transl Med. 2021 May 26;13(595):eabe8226. doi: 10.1126/scitranslmed.abe8226. Sci Transl Med. 2021. PMID: 34039740 Free PMC article.

8

Hypoxia-Reoxygenation Couples 3βHSD1 Enzyme and Cofactor Upregulation to Facilitate Androgen Biosynthesis and Hormone Therapy Resistance in Prostate Cancer.

Qin L, Chung YM, Berk M, Naelitz B, Zhu Z, Klein E, Chakraborty AA, Sharifi N. Qin L, et al. Among authors: zhu z. Cancer Res. 2022 Jul 5;82(13):2417-2430. doi: 10.1158/0008-5472.CAN-21-4256. Cancer Res. 2022. PMID: 35536859 Free PMC article.

9

Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression.

Qin L, Berk M, Chung YM, Cui D, Zhu Z, Chakraborty AA, Sharifi N. Qin L, et al. Among authors: zhu z. Cell Rep. 2024 Jan 23;43(1):113575. doi: 10.1016/j.celrep.2023.113575. Epub 2024 Jan 4. Cell Rep. 2024. PMID: 38181788 Free PMC article.

10

JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer.

Xiang Y, Zhu Z, Han G, Ye X, Xu B, Peng Z, Ma Y, Yu Y, Lin H, Chen AP, Chen CD. Xiang Y, et al. Among authors: zhu z. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19226-31. doi: 10.1073/pnas.0700735104. Epub 2007 Nov 28. Proc Natl Acad Sci U S A. 2007. PMID: 18048344 Free PMC article.

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