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MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells.
Wang X, Huang Z, Wu Q, Prager BC, Mack SC, Yang K, Kim LJY, Gimple RC, Shi Y, Lai S, Xie Q, Miller TE, Hubert CG, Song A, Dong Z, Zhou W, Fang X, Zhu Z, Mahadev V, Bao S, Rich JN. Wang X, et al. Among authors: zhu z. Cancer Res. 2017 Sep 15;77(18):4947-4960. doi: 10.1158/0008-5472.CAN-17-0114. Epub 2017 Jul 20. Cancer Res. 2017. PMID: 28729418 Free PMC article.
Zika virus has oncolytic activity against glioblastoma stem cells.
Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG. Zhu Z, et al. J Exp Med. 2017 Oct 2;214(10):2843-2857. doi: 10.1084/jem.20171093. Epub 2017 Sep 5. J Exp Med. 2017. PMID: 28874392 Free PMC article.
Correction: Zika virus has oncolytic activity against glioblastoma stem cells.
Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Tycksen E, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG. Zhu Z, et al. J Exp Med. 2017 Oct 2;214(10):3145. doi: 10.1084/jem.2017109309122017c. Epub 2017 Sep 15. J Exp Med. 2017. PMID: 28916645 Free PMC article. No abstract available.
Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression.
Wang X, Prager BC, Wu Q, Kim LJY, Gimple RC, Shi Y, Yang K, Morton AR, Zhou W, Zhu Z, Obara EAA, Miller TE, Song A, Lai S, Hubert CG, Jin X, Huang Z, Fang X, Dixit D, Tao W, Zhai K, Chen C, Dong Z, Zhang G, Dombrowski SM, Hamerlik P, Mack SC, Bao S, Rich JN. Wang X, et al. Among authors: zhu z. Cell Stem Cell. 2018 Apr 5;22(4):514-528.e5. doi: 10.1016/j.stem.2018.03.011. Cell Stem Cell. 2018. PMID: 29625067 Free PMC article.
Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus.
Bernatchez JA, Yang Z, Coste M, Li J, Beck S, Liu Y, Clark AE, Zhu Z, Luna LA, Sohl CD, Purse BW, Li R, Siqueira-Neto JL. Bernatchez JA, et al. Among authors: zhu z. Antimicrob Agents Chemother. 2018 Sep 24;62(10):e00725-18. doi: 10.1128/AAC.00725-18. Print 2018 Oct. Antimicrob Agents Chemother. 2018. PMID: 30061280 Free PMC article.
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma.
Mack SC, Singh I, Wang X, Hirsch R, Wu Q, Villagomez R, Bernatchez JA, Zhu Z, Gimple RC, Kim LJY, Morton A, Lai S, Qiu Z, Prager BC, Bertrand KC, Mah C, Zhou W, Lee C, Barnett GH, Vogelbaum MA, Sloan AE, Chavez L, Bao S, Scacheri PC, Siqueira-Neto JL, Lin CY, Rich JN. Mack SC, et al. Among authors: zhu z. J Exp Med. 2019 May 6;216(5):1071-1090. doi: 10.1084/jem.20190196. Epub 2019 Apr 4. J Exp Med. 2019. PMID: 30948495 Free PMC article.
Mechanism of Action of Methotrexate Against Zika Virus.
Beck S, Zhu Z, Oliveira MF, Smith DM, Rich JN, Bernatchez JA, Siqueira-Neto JL. Beck S, et al. Among authors: zhu z. Viruses. 2019 Apr 10;11(4):338. doi: 10.3390/v11040338. Viruses. 2019. PMID: 30974762 Free PMC article.
Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling.
Gimple RC, Kidwell RL, Kim LJY, Sun T, Gromovsky AD, Wu Q, Wolf M, Lv D, Bhargava S, Jiang L, Prager BC, Wang X, Ye Q, Zhu Z, Zhang G, Dong Z, Zhao L, Lee D, Bi J, Sloan AE, Mischel PS, Brown JM, Cang H, Huan T, Mack SC, Xie Q, Rich JN. Gimple RC, et al. Among authors: zhu z. Cancer Discov. 2019 Sep;9(9):1248-1267. doi: 10.1158/2159-8290.CD-19-0061. Epub 2019 Jun 14. Cancer Discov. 2019. PMID: 31201181 Free PMC article.
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells.
Wang X, Yang K, Wu Q, Kim LJY, Morton AR, Gimple RC, Prager BC, Shi Y, Zhou W, Bhargava S, Zhu Z, Jiang L, Tao W, Qiu Z, Zhao L, Zhang G, Li X, Agnihotri S, Mischel PS, Mack SC, Bao S, Rich JN. Wang X, et al. Among authors: zhu z. Sci Transl Med. 2019 Aug 7;11(504):eaau4972. doi: 10.1126/scitranslmed.aau4972. Sci Transl Med. 2019. PMID: 31391321 Free PMC article.
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