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GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision.
Asher WB, Terry DS, Gregorio GGA, Kahsai AW, Borgia A, Xie B, Modak A, Zhu Y, Jang W, Govindaraju A, Huang LY, Inoue A, Lambert NA, Gurevich VV, Shi L, Lefkowitz RJ, Blanchard SC, Javitch JA. Asher WB, et al. Among authors: zhu y. Cell. 2022 May 12;185(10):1661-1675.e16. doi: 10.1016/j.cell.2022.03.042. Epub 2022 Apr 27. Cell. 2022. PMID: 35483373 Free PMC article.
Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing.
Andrianarivelo A, Saint-Jour E, Pousinha P, Fernandez SP, Petitbon A, De Smedt-Peyrusse V, Heck N, Ortiz V, Allichon MC, Kappès V, Betuing S, Walle R, Zhu Y, Joséphine C, Bemelmans AP, Turecki G, Mechawar N, Javitch JA, Caboche J, Trifilieff P, Barik J, Vanhoutte P. Andrianarivelo A, et al. Among authors: zhu y. Sci Adv. 2021 Oct 22;7(43):eabg5970. doi: 10.1126/sciadv.abg5970. Epub 2021 Oct 20. Sci Adv. 2021. PMID: 34669474 Free PMC article.
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