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Structural and functional insights into a novel pre-clinical-stage antibody targeting IL-17A for treatment of autoimmune diseases.
Xu JG, Jia H, Chen S, Xu J, Zhan Y, Yu H, Wang W, Kang X, Cui X, Feng Y, Chen X, Xu W, Pan X, Wei X, Li H, Wang Y, Xia S, Liu X, Yang L, He Y, Zhu X. Xu JG, et al. Among authors: zhu x. Int J Biol Macromol. 2022 Mar 31;202:529-538. doi: 10.1016/j.ijbiomac.2022.01.119. Epub 2022 Jan 20. Int J Biol Macromol. 2022. PMID: 35066019 Free article.
Safety, tolerability, pharmacokinetics and efficacy of HB0017, a humanized monoclonal antibody that targets interleukin-17A, in healthy participants and patients with moderate-to-severe plaque psoriasis.
Jiang C, Du Y, Liu X, Wang J, Ge C, Xu J, Wang S, Li B, Zhu G, Zhang W, Qian Q, Ma C, Zhu X, Zhan Y, Yang Y. Jiang C, et al. Among authors: zhu g, zhu x. Br J Dermatol. 2023 Dec 20;190(1):28-36. doi: 10.1093/bjd/ljad315. Br J Dermatol. 2023. PMID: 37669307 Clinical Trial.
A Randomized, Double-Blind, Single-Dose Study Comparing the Biosimilarity of HOT-1010 With Bevacizumab (Avastin®) in Chinese Healthy Male Subjects.
Huang K, Que L, Ding Y, Chu N, Qian Z, Shi Y, Qin W, Li Z, Chen Y, Gu X, Wang J, Zhang L, Zhang J, Zhu X, Yang Y, Tang Y, He Q. Huang K, et al. Among authors: zhu x. Front Pharmacol. 2021 Jun 17;12:694375. doi: 10.3389/fphar.2021.694375. eCollection 2021. Front Pharmacol. 2021. PMID: 34220519 Free PMC article.
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