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Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
Xu X, Zhu XP, Bai JY, Xia P, Li Y, Lu Y, Li XY, Gao X. Xu X, et al. Among authors: zhu xp. FASEB J. 2019 Jun;33(6):7289-7300. doi: 10.1096/fj.201802316R. Epub 2019 Mar 8. FASEB J. 2019. PMID: 30848932
These results suggested that BBR alleviates HFD-induced inhibition of fatty acid beta-OX partly through SIRT3-mediated LCAD deacetylation, which may provide a novel mechanism and support BBR as a promising therapeutic for NAFLD.-Xu, X., Zhu, X.-P., Bai, J.-Y. …
These results suggested that BBR alleviates HFD-induced inhibition of fatty acid beta-OX partly through SIRT3-mediated LCAD deacetylation, w …
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