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A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry.
Xu M, Pradhan M, Gorshkov K, Petersen JD, Shen M, Guo H, Zhu W, Klumpp-Thomas C, Michael S, Itkin M, Itkin Z, Straus MR, Zimmerberg J, Zheng W, Whittaker GR, Chen CZ. Xu M, et al. Among authors: zhu w. SLAS Discov. 2022 Mar;27(2):86-94. doi: 10.1016/j.slasd.2021.12.005. Epub 2022 Jan 2. SLAS Discov. 2022. PMID: 35086793 Free PMC article.
Identifying SARS-CoV-2 Entry Inhibitors through Drug Repurposing Screens of SARS-S and MERS-S Pseudotyped Particles.
Chen CZ, Xu M, Pradhan M, Gorshkov K, Petersen JD, Straus MR, Zhu W, Shinn P, Guo H, Shen M, Klumpp-Thomas C, Michael SG, Zimmerberg J, Zheng W, Whittaker GR. Chen CZ, et al. Among authors: zhu w. ACS Pharmacol Transl Sci. 2020 Oct 19;3(6):1165-1175. doi: 10.1021/acsptsci.0c00112. eCollection 2020 Dec 11. ACS Pharmacol Transl Sci. 2020. PMID: 33330839 Free PMC article.
The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules.
Gorshkov K, Chen CZ, Bostwick R, Rasmussen L, Tran BN, Cheng YS, Xu M, Pradhan M, Henderson M, Zhu W, Oh E, Susumu K, Wolak M, Shamim K, Huang W, Hu X, Shen M, Klumpp-Thomas C, Itkin Z, Shinn P, Carlos de la Torre J, Simeonov A, Michael SG, Hall MD, Lo DC, Zheng W. Gorshkov K, et al. Among authors: zhu w. ACS Infect Dis. 2021 Jun 11;7(6):1389-1408. doi: 10.1021/acsinfecdis.0c00349. Epub 2020 Dec 21. ACS Infect Dis. 2021. PMID: 33346633 Free PMC article.
The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators.
Gorshkov K, Chen CZ, Bostwick R, Rasmussen L, Xu M, Pradhan M, Tran BN, Zhu W, Shamim K, Huang W, Hu X, Shen M, Klumpp-Thomas C, Itkin Z, Shinn P, Simeonov A, Michael S, Hall MD, Lo DC, Zheng W. Gorshkov K, et al. Among authors: zhu w. bioRxiv [Preprint]. 2020 May 28:2020.05.16.091520. doi: 10.1101/2020.05.16.091520. bioRxiv. 2020. PMID: 32511355 Free PMC article. Updated. Preprint.
Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles.
Chen CZ, Xu M, Pradhan M, Gorshkov K, Petersen J, Straus MR, Zhu W, Shinn P, Guo H, Shen M, Klumpp-Thomas C, Michael SG, Zimmerberg J, Zheng W, Whittaker GR. Chen CZ, et al. Among authors: zhu w. bioRxiv [Preprint]. 2020 Aug 18:2020.07.10.197988. doi: 10.1101/2020.07.10.197988. bioRxiv. 2020. PMID: 32839777 Free PMC article. Updated. Preprint.
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