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Small molecule selectively suppresses MYC transcription in cancer cells.
Bouvard C, Lim SM, Ludka J, Yazdani N, Woods AK, Chatterjee AK, Schultz PG, Zhu S. Bouvard C, et al. Among authors: zhu s. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3497-3502. doi: 10.1073/pnas.1702663114. Epub 2017 Mar 14. Proc Natl Acad Sci U S A. 2017. PMID: 28292893 Free PMC article.
Small molecule-based approaches to adult stem cell therapies.
Lairson LL, Lyssiotis CA, Zhu S, Schultz PG. Lairson LL, et al. Among authors: zhu s. Annu Rev Pharmacol Toxicol. 2013;53:107-25. doi: 10.1146/annurev-pharmtox-011112-140300. Annu Rev Pharmacol Toxicol. 2013. PMID: 23294307 Review.
Reversine increases the plasticity of lineage-committed mammalian cells.
Chen S, Takanashi S, Zhang Q, Xiong W, Zhu S, Peters EC, Ding S, Schultz PG. Chen S, et al. Among authors: zhu s. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10482-7. doi: 10.1073/pnas.0704360104. Epub 2007 Jun 12. Proc Natl Acad Sci U S A. 2007. PMID: 17566101 Free PMC article.
A genomic screen identifies TYRO3 as a MITF regulator in melanoma.
Zhu S, Wurdak H, Wang Y, Galkin A, Tao H, Li J, Lyssiotis CA, Yan F, Tu BP, Miraglia L, Walker J, Sun F, Orth A, Schultz PG, Wu X. Zhu S, et al. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17025-30. doi: 10.1073/pnas.0909292106. Epub 2009 Sep 23. Proc Natl Acad Sci U S A. 2009. PMID: 19805117 Free PMC article.
A small molecule accelerates neuronal differentiation in the adult rat.
Wurdak H, Zhu S, Min KH, Aimone L, Lairson LL, Watson J, Chopiuk G, Demas J, Charette B, Halder R, Weerapana E, Cravatt BF, Cline HT, Peters EC, Zhang J, Walker JR, Wu C, Chang J, Tuntland T, Cho CY, Schultz PG. Wurdak H, et al. Among authors: zhu s. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16542-7. doi: 10.1073/pnas.1010300107. Epub 2010 Sep 7. Proc Natl Acad Sci U S A. 2010. PMID: 20823227 Free PMC article.
An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.
Wurdak H, Zhu S, Romero A, Lorger M, Watson J, Chiang CY, Zhang J, Natu VS, Lairson LL, Walker JR, Trussell CM, Harsh GR, Vogel H, Felding-Habermann B, Orth AP, Miraglia LJ, Rines DR, Skirboll SL, Schultz PG. Wurdak H, et al. Among authors: zhu s. Cell Stem Cell. 2010 Jan 8;6(1):37-47. doi: 10.1016/j.stem.2009.11.002. Cell Stem Cell. 2010. PMID: 20085741 Free article.
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