Zhu L - Search Results

1

Tryptophan-Centric Bioinformatics Identifies New Lasso Peptide Modifications.

Harris LA, Saad H, Shelton KE, Zhu L, Guo X, Mitchell DA. Harris LA, et al. Among authors: zhu l. Biochemistry. 2024 Apr 2;63(7):865-879. doi: 10.1021/acs.biochem.4c00035. Epub 2024 Mar 18. Biochemistry. 2024. PMID: 38498885

2

Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete.

Metelev M, Tietz JI, Melby JO, Blair PM, Zhu L, Livnat I, Severinov K, Mitchell DA. Metelev M, et al. Among authors: zhu l. Chem Biol. 2015 Feb 19;22(2):241-50. doi: 10.1016/j.chembiol.2014.11.017. Epub 2015 Jan 15. Chem Biol. 2015. PMID: 25601074 Free PMC article.

3

Reactivity-Based Screening for Citrulline-Containing Natural Products Reveals a Family of Bacterial Peptidyl Arginine Deiminases.

Harris LA, Saint-Vincent PMB, Guo X, Hudson GA, DiCaprio AJ, Zhu L, Mitchell DA. Harris LA, et al. Among authors: zhu l. ACS Chem Biol. 2020 Dec 18;15(12):3167-3175. doi: 10.1021/acschembio.0c00685. Epub 2020 Nov 29. ACS Chem Biol. 2020. PMID: 33249828 Free PMC article.

4

A scalable platform to discover antimicrobials of ribosomal origin.

Ayikpoe RS, Shi C, Battiste AJ, Eslami SM, Ramesh S, Simon MA, Bothwell IR, Lee H, Rice AJ, Ren H, Tian Q, Harris LA, Sarksian R, Zhu L, Frerk AM, Precord TW, van der Donk WA, Mitchell DA, Zhao H. Ayikpoe RS, et al. Among authors: zhu l. Nat Commun. 2022 Oct 17;13(1):6135. doi: 10.1038/s41467-022-33890-w. Nat Commun. 2022. PMID: 36253467 Free PMC article.

5

Peptidase Activation by a Leader Peptide-Bound RiPP Recognition Element.

Kretsch AM, Gadgil MG, DiCaprio AJ, Barrett SE, Kille BL, Si Y, Zhu L, Mitchell DA. Kretsch AM, et al. Among authors: zhu l. Biochemistry. 2023 Feb 21;62(4):956-967. doi: 10.1021/acs.biochem.2c00700. Epub 2023 Feb 3. Biochemistry. 2023. PMID: 36734655 Free PMC article.

6

Genome mining unveils a class of ribosomal peptides with two amino termini.

Ren H, Dommaraju SR, Huang C, Cui H, Pan Y, Nesic M, Zhu L, Sarlah D, Mitchell DA, Zhao H. Ren H, et al. Among authors: zhu l. bioRxiv [Preprint]. 2023 Mar 8:2023.03.08.531785. doi: 10.1101/2023.03.08.531785. bioRxiv. 2023. PMID: 36945508 Free PMC article. Updated. Preprint.

7

Genome mining unveils a class of ribosomal peptides with two amino termini.

Ren H, Dommaraju SR, Huang C, Cui H, Pan Y, Nesic M, Zhu L, Sarlah D, Mitchell DA, Zhao H. Ren H, et al. Among authors: zhu l. Nat Commun. 2023 Mar 23;14(1):1624. doi: 10.1038/s41467-023-37287-1. Nat Commun. 2023. PMID: 36959188 Free PMC article.

8

Biosynthesis of macrocyclic peptides with C-terminal β-amino-α-keto acid groups by three different metalloenzymes.

Nguyen DT, Zhu L, Gray DL, Woods TJ, Padhi C, Flatt KM, Mitchell DA, van der Donk WA. Nguyen DT, et al. Among authors: zhu l. bioRxiv [Preprint]. 2024 Jan 17:2023.10.30.564719. doi: 10.1101/2023.10.30.564719. bioRxiv. 2024. PMID: 37965205 Free PMC article. Preprint.

9

Core-dependent post-translational modifications guide the biosynthesis of a new class of hypermodified peptides.

Pei ZF, Zhu L, Nair SK. Pei ZF, et al. Among authors: zhu l. Nat Commun. 2023 Nov 25;14(1):7734. doi: 10.1038/s41467-023-43604-5. Nat Commun. 2023. PMID: 38007494 Free PMC article.

10

Substrate Recognition by the Class II Lanthipeptide Synthetase HalM2.

Rahman IR, Acedo JZ, Liu XR, Zhu L, Arrington J, Gross ML, van der Donk WA. Rahman IR, et al. Among authors: zhu l. ACS Chem Biol. 2020 Jun 19;15(6):1473-1486. doi: 10.1021/acschembio.0c00127. Epub 2020 Apr 28. ACS Chem Biol. 2020. PMID: 32293871 Free PMC article.

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