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Dual-AAV vector-mediated expression of MYO7A improves vestibular function in a mouse model of Usher syndrome 1B.
Lau SC, Grati M, Isgrig K, Sinan M, Calabro KR, Zhu J, Ishibashi Y, Ozgur Z, Wafa T, Belyantseva IA, Fitzgerald T, Friedman TB, Boye SL, Boye SE, Chien WW. Lau SC, et al. Among authors: zhu j. Mol Ther Methods Clin Dev. 2023 Aug 21;30:534-545. doi: 10.1016/j.omtm.2023.08.012. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37693946 Free PMC article.
AAV2.7m8 is a powerful viral vector for inner ear gene therapy.
Isgrig K, McDougald DS, Zhu J, Wang HJ, Bennett J, Chien WW. Isgrig K, et al. Among authors: zhu j. Nat Commun. 2019 Jan 25;10(1):427. doi: 10.1038/s41467-018-08243-1. Nat Commun. 2019. PMID: 30683875 Free PMC article.
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