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Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia.
Barth BM, Wang W, Toran PT, Fox TE, Annageldiyev C, Ondrasik RM, Keasey NR, Brown TJ, Devine VG, Sullivan EC, Cote AL, Papakotsi V, Tan SF, Shanmugavelandy SS, Deering TG, Needle DB, Stern ST, Zhu J, Liao J, Viny AD, Feith DJ, Levine RL, Wang HG, Loughran TP Jr, Sharma A, Kester M, Claxton DF. Barth BM, et al. Among authors: zhu j. Blood Adv. 2019 Sep 10;3(17):2598-2603. doi: 10.1182/bloodadvances.2018021295. Blood Adv. 2019. PMID: 31488436 Free PMC article.
Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
Tan SF, Liu X, Fox TE, Barth BM, Sharma A, Turner SD, Awwad A, Dewey A, Doi K, Spitzer B, Shah MV, Morad SA, Desai D, Amin S, Zhu J, Liao J, Yun J, Kester M, Claxton DF, Wang HG, Cabot MC, Schuchman EH, Levine RL, Feith DJ, Loughran TP Jr. Tan SF, et al. Among authors: zhu j. Oncotarget. 2016 Dec 13;7(50):83208-83222. doi: 10.18632/oncotarget.13079. Oncotarget. 2016. PMID: 27825124 Free PMC article.
A phase I clinical trial of avelumab in combination with decitabine as first line treatment of unfit patients with acute myeloid leukemia.
Zheng H, Mineishi S, Claxton D, Zhu J, Zhao C, Jia B, Ehmann WC, Rybka WB, Naik S, Songdej N, Drabick JJ, Hohl RJ. Zheng H, et al. Among authors: zhu j. Am J Hematol. 2021 Feb 1;96(2):E46-E50. doi: 10.1002/ajh.26043. Epub 2020 Nov 23. Am J Hematol. 2021. PMID: 33146922 Free PMC article. Clinical Trial. No abstract available.
Clinico-pathological correlation of serial measurement of circulating tumor cells in 24 metastatic colorectal cancer patients receiving chemotherapy reveals interpatient heterogeneity correlated with CEA levels but independent of KRAS and BRAF mutation.
Das A, Kunkel M, Joudeh J, Dicker DT, Scicchitano A, Allen JE, Sarwani N, Yang Z, Kaifi J, Zhu J, Liao J, El-Deiry WS. Das A, et al. Among authors: zhu j. Cancer Biol Ther. 2015;16(5):709-13. doi: 10.1080/15384047.2015.1030555. Cancer Biol Ther. 2015. PMID: 25806877 Free PMC article.
Reduced nicotine content cigarettes in smokers of low socioeconomic status: study protocol for a randomized control trial.
Krebs NM, Allen SI, Veldheer S, Martinez DJ, Horn K, Livelsberger C, Modesto J, Kuprewicz R, Wilhelm A, Hrabovsky S, Kazi A, Fazzi A, Liao J, Zhu J, Wasserman E, Reilly SM, Reinhart L, Trushin N, Moyer RE, Bascom R, Foulds J, Richie JP Jr, Muscat JE. Krebs NM, et al. Among authors: zhu j. Trials. 2017 Jul 3;18(1):300. doi: 10.1186/s13063-017-2038-9. Trials. 2017. PMID: 28673312 Free PMC article. Clinical Trial.
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