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Analysis of the binding sites of vitamin D 1α-hydroxylase (CYP27B1) and vitamin D 24-hydroxylase (CYP24A1) for the design of selective CYP24A1 inhibitors: Homology modelling, molecular dynamics simulations and identification of key binding requirements.
Taban IM, Zhu J, DeLuca HF, Simons C. Taban IM, et al. Among authors: zhu j. Bioorg Med Chem. 2017 Oct 15;25(20):5629-5636. doi: 10.1016/j.bmc.2017.08.036. Epub 2017 Aug 22. Bioorg Med Chem. 2017. PMID: 28886997
Pharmacokinetics of a New Oral Vitamin D Receptor Activator (2-Methylene-19-Nor-(20S)-1α,25-Dihydroxyvitamin D3) in Patients with Chronic Kidney Disease and Secondary Hyperparathyroidism on Hemodialysis.
Pandey R, Zella JB, Zhu JG, Plum LA, Clagett-Dame M, Blaser WJ, Bedale W, DeLuca HF, Coyne DW. Pandey R, et al. Among authors: zhu jg. Drugs R D. 2017 Dec;17(4):597-605. doi: 10.1007/s40268-017-0210-z. Drugs R D. 2017. PMID: 28905271 Free PMC article. Clinical Trial.
Where is the vitamin D receptor?
Wang Y, Zhu J, DeLuca HF. Wang Y, et al. Among authors: zhu j. Arch Biochem Biophys. 2012 Jul 1;523(1):123-33. doi: 10.1016/j.abb.2012.04.001. Epub 2012 Apr 6. Arch Biochem Biophys. 2012. PMID: 22503810 Review.
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