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Pharmacological inhibition of LSD1 suppresses growth of hepatocellular carcinoma by inducing GADD45B.
Sang N, Zhong X, Gou K, Liu H, Xu J, Zhou Y, Zhou X, Liu Y, Chen Z, Zhou Y, Li Y, Tao L, Su N, Zhou L, Qiu J, Yang X, Zuo Z, Fu L, Zhang J, Li D, Li C, Sun Q, Lei J, Li R, Yang S, Cen X, Zhao Y. Sang N, et al. Among authors: zhou x, zhou y, zhou l. MedComm (2020). 2023 May 24;4(3):e269. doi: 10.1002/mco2.269. eCollection 2023 Jun. MedComm (2020). 2023. PMID: 37250145 Free PMC article.
Bifunctional Naphtho[2,3-d][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production.
Zuo Z, Liu X, Qian X, Zeng T, Sang N, Liu H, Zhou Y, Tao L, Zhou X, Su N, Yu Y, Chen Q, Luo Y, Zhao Y. Zuo Z, et al. Among authors: zhou x, zhou y. J Med Chem. 2020 Jul 23;63(14):7633-7652. doi: 10.1021/acs.jmedchem.0c00512. Epub 2020 Jul 1. J Med Chem. 2020. PMID: 32496056
Correction to "Bifunctional Naphtho[2,3-d][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production".
Zuo Z, Liu X, Qian X, Zeng T, Sang N, Liu H, Zhou Y, Tao L, Zhou X, Su N, Yu Y, Chen Q, Luo Y, Zhao Y. Zuo Z, et al. Among authors: zhou x, zhou y. J Med Chem. 2020 Sep 24;63(18):10532. doi: 10.1021/acs.jmedchem.0c01455. Epub 2020 Sep 14. J Med Chem. 2020. PMID: 32924476 No abstract available.
DHODH and cancer: promising prospects to be explored.
Zhou Y, Tao L, Zhou X, Zuo Z, Gong J, Liu X, Zhou Y, Liu C, Sang N, Liu H, Zou J, Gou K, Yang X, Zhao Y. Zhou Y, et al. Among authors: zhou x. Cancer Metab. 2021 May 10;9(1):22. doi: 10.1186/s40170-021-00250-z. Cancer Metab. 2021. PMID: 33971967 Free PMC article. Review.
Design, Synthesis, and Biological Evaluation of a Novel Series of Teriflunomide Derivatives as Potent Human Dihydroorotate Dehydrogenase Inhibitors for Malignancy Treatment.
Li C, Yang X, Luo Y, Liu H, Zhong X, Zhou X, Zeng T, Tao L, Zhou Y, Gou K, Yang X, Liu X, Chen Q, Zhao Y, Luo Y. Li C, et al. Among authors: zhou x, zhou y. J Med Chem. 2021 Dec 23;64(24):18175-18192. doi: 10.1021/acs.jmedchem.1c01711. Epub 2021 Dec 14. J Med Chem. 2021. PMID: 34905371
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