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PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosis.
Zhang Y, Shen L, Zhu H, Dreissigacker K, Distler D, Zhou X, Györfi AH, Bergmann C, Meng X, Dees C, Trinh-Minh T, Ludolph I, Horch R, Ramming A, Schett G, Distler JHW. Zhang Y, et al. Among authors: zhou x. Ann Rheum Dis. 2020 Sep;79(9):1227-1233. doi: 10.1136/annrheumdis-2020-216963. Epub 2020 Jun 1. Ann Rheum Dis. 2020. PMID: 32482644
Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis.
Chakraborty D, Zhu H, Jüngel A, Summa L, Li YN, Matei AE, Zhou X, Huang J, Trinh-Minh T, Chen CW, Lafyatis R, Dees C, Bergmann C, Soare A, Luo H, Ramming A, Schett G, Distler O, Distler JHW. Chakraborty D, et al. Among authors: zhou x. Sci Transl Med. 2020 Sep 30;12(563):eaaz5506. doi: 10.1126/scitranslmed.aaz5506. Sci Transl Med. 2020. PMID: 32998972
X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc).
Bergmann C, Hallenberger L, Chenguiti Fakhouri S, Merlevede B, Brandt A, Dees C, Zhu H, Zehender A, Zhou X, Schwab A, Chen CW, Györfi AH, Matei AE, Chakraborty D, Trinh-Minh T, Rauber S, Coras R, Bozec A, Kreuter A, Ziemer M, Schett G, Distler JHW. Bergmann C, et al. Among authors: zhou x. Ann Rheum Dis. 2021 Aug;80(8):1048-1056. doi: 10.1136/annrheumdis-2020-219822. Epub 2021 Apr 26. Ann Rheum Dis. 2021. PMID: 33903093
Effect of Anti-S100A4 Monoclonal Antibody Treatment on Experimental Skin Fibrosis and Systemic Sclerosis-Specific Transcriptional Signatures in Human Skin.
Trinh-Minh T, Györfi AH, Tomcik M, Tran-Manh C, Zhou X, Dickel N, Tümerdem BS, Kreuter A, Burmann SN, Borchert SV, Hussain RI, Hallén J, Klingelhöfer J, Kunz M, Distler JHW. Trinh-Minh T, et al. Among authors: zhou x. Arthritis Rheumatol. 2024 May;76(5):783-795. doi: 10.1002/art.42781. Epub 2024 Feb 15. Arthritis Rheumatol. 2024. PMID: 38108109
Attenuation of fibroblast activation and fibrosis by adropin in systemic sclerosis.
Liang M, Dickel N, Györfi AH, SafakTümerdem B, Li YN, Rigau AR, Liang C, Hong X, Shen L, Matei AE, Trinh-Minh T, Tran-Manh C, Zhou X, Zehender A, Kreuter A, Zou H, Schett G, Kunz M, Distler JHW. Liang M, et al. Among authors: zhou x. Sci Transl Med. 2024 Mar 27;16(740):eadd6570. doi: 10.1126/scitranslmed.add6570. Epub 2024 Mar 27. Sci Transl Med. 2024. PMID: 38536934
Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis.
Grönberg C, Rattik S, Tran-Manh C, Zhou X, Rius Rigau A, Li YN, Györfi AH, Dickel N, Kunz M, Kreuter A, Matei EA, Zhu H, Skoog P, Liberg D, Distler JH, Trinh-Minh T. Grönberg C, et al. Among authors: zhou x. Ann Rheum Dis. 2024 Apr 9:ard-2023-225158. doi: 10.1136/ard-2023-225158. Online ahead of print. Ann Rheum Dis. 2024. PMID: 38594058 Free article.
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