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Page 1
Discovery of a novel class of potent and orally bioavailable sphingosine 1-phosphate receptor 1 antagonists.
Ibrahim MA, Johnson HW, Jeong JW, Lewis GL, Shi X, Noguchi RT, Williams M, Leahy JW, Nuss JM, Woolfrey J, Banica M, Bentzien F, Chou YC, Gibson A, Heald N, Lamb P, Mattheakis L, Matthews D, Shipway A, Wu X, Zhang W, Zhou S, Shankar G. Ibrahim MA, et al. Among authors: zhou s. J Med Chem. 2012 Feb 9;55(3):1368-81. doi: 10.1021/jm201533b. Epub 2012 Jan 24. J Med Chem. 2012. PMID: 22214363
RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates.
Yin G, Stephenson HT, Yang J, Li X, Armstrong SM, Heibeck TH, Tran C, Masikat MR, Zhou S, Stafford RL, Yam AY, Lee J, Steiner AR, Gill A, Penta K, Pollitt S, Baliga R, Murray CJ, Thanos CD, McEvoy LM, Sato AK, Hallam TJ. Yin G, et al. Among authors: zhou s. Sci Rep. 2017 Jun 8;7(1):3026. doi: 10.1038/s41598-017-03192-z. Sci Rep. 2017. PMID: 28596531 Free PMC article.
Toward a Ferrous Iron-Cleavable Linker for Antibody-Drug Conjugates.
Spangler B, Kline T, Hanson J, Li X, Zhou S, Wells JA, Sato AK, Renslo AR. Spangler B, et al. Among authors: zhou s. Mol Pharm. 2018 May 7;15(5):2054-2059. doi: 10.1021/acs.molpharmaceut.8b00242. Epub 2018 Mar 23. Mol Pharm. 2018. PMID: 29569925
Development of an E. coli strain for cell-free ADC manufacturing.
Groff D, Carlos NA, Chen R, Hanson JA, Liang S, Armstrong S, Li X, Zhou S, Steiner A, Hallam TJ, Yin G. Groff D, et al. Among authors: zhou s. Biotechnol Bioeng. 2022 Jan;119(1):162-175. doi: 10.1002/bit.27961. Epub 2021 Oct 25. Biotechnol Bioeng. 2022. PMID: 34655229 Free PMC article.
Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers.
Li X, Zhou S, Abrahams CL, Krimm S, Smith J, Bajjuri K, Stephenson HT, Henningsen R, Hanson J, Heibeck TH, Calarese D, Tran C, Yin G, Stafford RL, Yam AY, Kline T, De Almeida VI, Sato AK, Lupher M, Bedard K, Hallam TJ. Li X, et al. Among authors: zhou s. Mol Cancer Ther. 2023 Feb 1;22(2):155-167. doi: 10.1158/1535-7163.MCT-22-0322. Mol Cancer Ther. 2023. PMID: 36459691 Free PMC article.
Production of antibodies and antibody fragments containing non-natural amino acids in Escherichia coli.
Blake-Hedges J, Groff D, Foo W, Hanson J, Castillo E, Wen M, Cheung D, Masikat MR, Lu J, Park Y, Carlos NA, Usman H, Fong K, Yu A, Zhou S, Kwong J, Tran C, Li X, Yuan D, Hallam T, Yin G. Blake-Hedges J, et al. Among authors: zhou s. MAbs. 2024 Jan-Dec;16(1):2316872. doi: 10.1080/19420862.2024.2316872. Epub 2024 Feb 21. MAbs. 2024. PMID: 38381460 Free PMC article.
Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death.
Milutinovic S, Kashyap AK, Yanagi T, Wimer C, Zhou S, O'Neil R, Kurtzman AL, Faynboym A, Xu L, Hannum CH, Diaz PW, Matsuzawa S, Horowitz M, Horowitz L, Bhatt RR, Reed JC. Milutinovic S, et al. Among authors: zhou s. Mol Cancer Ther. 2016 Jan;15(1):114-24. doi: 10.1158/1535-7163.MCT-15-0400. Epub 2015 Oct 29. Mol Cancer Ther. 2016. PMID: 26516157 Free PMC article.
Results of a Pilot External Quality Assessment Scheme for Genetic Testing of Newborns with Spinal Muscular Atrophy.
Wang W, Wu L, Hui Y, Du Y, Yang J, Jiang P, Gu M, He H, Qiu L, Zhang Z, Gao L, Lin C, Jiang J, He X, Miao J, Li Y, Luo Z, Zhang H, Liu Y, Li L, Li X, Gan X, Mou K, Liang H, Shi A, Zhou S, Huang X, Sun L, Wan T, Ji G, Tang K, Ye Q, Sun Z, Dai Z, Du Y, Wang X, Yang Y, Xiong H, Wang Z. Wang W, et al. Among authors: zhou s. Clin Lab. 2024 May 1;70(5). doi: 10.7754/Clin.Lab.2023.230907. Clin Lab. 2024. PMID: 38747911
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