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A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs.
Liu Z, Zhou J, Xu W, Deng W, Wang Y, Wang M, Wang Q, Hsieh M, Dong J, Wang X, Huang W, Xing L, He M, Tao C, Xie Y, Zhang Y, Wang Y, Zhao J, Yuan Z, Qin C, Jiang S, Lu L. Liu Z, et al. Among authors: zhou j. Cell Res. 2022 Mar;32(3):269-287. doi: 10.1038/s41422-022-00612-2. Epub 2022 Jan 19. Cell Res. 2022. PMID: 35046518 Free PMC article.
MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2.
Yeung ML, Yao Y, Jia L, Chan JF, Chan KH, Cheung KF, Chen H, Poon VK, Tsang AK, To KK, Yiu MK, Teng JL, Chu H, Zhou J, Zhang Q, Deng W, Lau SK, Lau JY, Woo PC, Chan TM, Yung S, Zheng BJ, Jin DY, Mathieson PW, Qin C, Yuen KY. Yeung ML, et al. Among authors: zhou j. Nat Microbiol. 2016 Feb 22;1(3):16004. doi: 10.1038/nmicrobiol.2016.4. Nat Microbiol. 2016. PMID: 27572168 Free PMC article.
Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies.
Zhou D, Chan JF, Zhou B, Zhou R, Li S, Shan S, Liu L, Zhang AJ, Chen SJ, Chan CC, Xu H, Poon VK, Yuan S, Li C, Chik KK, Chan CC, Cao J, Chan CY, Kwan KY, Du Z, Lau TT, Zhang Q, Zhou J, To KK, Zhang L, Ho DD, Yuen KY, Chen Z. Zhou D, et al. Among authors: zhou j, zhou b, zhou r. Cell Host Microbe. 2021 Apr 14;29(4):551-563.e5. doi: 10.1016/j.chom.2021.02.019. Epub 2021 Feb 25. Cell Host Microbe. 2021. PMID: 33657424 Free PMC article.
Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection.
Lan Q, Pu J, Cai Y, Zhou J, Wang L, Jiao F, Xu W, Wang Q, Xia S, Lu L, Jiang S. Lan Q, et al. Among authors: zhou j. Microbes Infect. 2021 Sep-Oct;23(8):104840. doi: 10.1016/j.micinf.2021.104840. Epub 2021 May 20. Microbes Infect. 2021. PMID: 34022374 Free PMC article. No abstract available.
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation.
Xia S, Lan Q, Zhu Y, Wang C, Xu W, Li Y, Wang L, Jiao F, Zhou J, Hua C, Wang Q, Cai X, Wu Y, Gao J, Liu H, Sun G, Münch J, Kirchhoff F, Yuan Z, Xie Y, Sun F, Jiang S, Lu L. Xia S, et al. Among authors: zhou j. Signal Transduct Target Ther. 2021 Jul 29;6(1):288. doi: 10.1038/s41392-021-00712-2. Signal Transduct Target Ther. 2021. PMID: 34326308 Free PMC article.
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