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Dicoumarol, an NQO1 inhibitor, blocks cccDNA transcription by promoting degradation of HBx.
Cheng ST, Hu JL, Ren JH, Yu HB, Zhong S, Wai Wong VK, Kwan Law BY, Chen WX, Xu HM, Zhang ZZ, Cai XF, Hu Y, Zhang WL, Long QX, Ren F, Zhou HZ, Huang AL, Chen J. Cheng ST, et al. Among authors: zhong s. J Hepatol. 2021 Mar;74(3):522-534. doi: 10.1016/j.jhep.2020.09.019. Epub 2020 Sep 25. J Hepatol. 2021. PMID: 32987030 Free article.
SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome.
Yu HB, Cheng ST, Ren F, Chen Y, Shi XF, Wong VKW, Law BYK, Ren JH, Zhong S, Chen WX, Xu HM, Zhang ZZ, Hu JL, Cai XF, Hu Y, Zhang WL, Long QX, He L, Hu ZW, Jiang H, Zhou HZ, Huang AL, Chen J. Yu HB, et al. Among authors: zhong s. Clin Sci (Lond). 2021 Jun 25;135(12):1505-1522. doi: 10.1042/CS20210392. Clin Sci (Lond). 2021. PMID: 34128977
[Antiviral activities of ISG20 against hepatitis C virus].
Xu H, Lei Y, Zhong S, Peng FY, Zhou Z, Li K, Ren H. Xu H, et al. Among authors: zhong s. Zhonghua Gan Zang Bing Za Zhi. 2013 Jan;21(1):33-7. doi: 10.3760/cma.j.issn.1007-3418.2013.01.010. Zhonghua Gan Zang Bing Za Zhi. 2013. PMID: 23663760 Chinese.
4,217 results