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Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species.
Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD, Srivastava D, Ocorr K, Bruneau BG, Bodmer R. Qian L, et al. Among authors: zheng y. J Cell Biol. 2011 Jun 27;193(7):1181-96. doi: 10.1083/jcb.201006114. Epub 2011 Jun 20. J Cell Biol. 2011. PMID: 21690310 Free PMC article.
Cdc42 is an antihypertrophic molecular switch in the mouse heart.
Maillet M, Lynch JM, Sanna B, York AJ, Zheng Y, Molkentin JD. Maillet M, et al. Among authors: zheng y. J Clin Invest. 2009 Oct;119(10):3079-88. doi: 10.1172/JCI37694. Epub 2009 Sep 8. J Clin Invest. 2009. PMID: 19741299 Free PMC article.
RhoA protects the mouse heart against ischemia/reperfusion injury.
Xiang SY, Vanhoutte D, Del Re DP, Purcell NH, Ling H, Banerjee I, Bossuyt J, Lang RA, Zheng Y, Matkovich SJ, Miyamoto S, Molkentin JD, Dorn GW 2nd, Brown JH. Xiang SY, et al. Among authors: zheng y. J Clin Invest. 2011 Aug;121(8):3269-76. doi: 10.1172/JCI44371. Epub 2011 Jul 11. J Clin Invest. 2011. PMID: 21747165 Free PMC article.
Rho GTPase-activating proteins in cell regulation.
Moon SY, Zheng Y. Moon SY, et al. Among authors: zheng y. Trends Cell Biol. 2003 Jan;13(1):13-22. doi: 10.1016/s0962-8924(02)00004-1. Trends Cell Biol. 2003. PMID: 12480336 Review.
Rho GTPase regulation by miRNAs and covalent modifications.
Liu M, Bi F, Zhou X, Zheng Y. Liu M, et al. Among authors: zheng y. Trends Cell Biol. 2012 Jul;22(7):365-73. doi: 10.1016/j.tcb.2012.04.004. Epub 2012 May 7. Trends Cell Biol. 2012. PMID: 22572609 Free PMC article. Review.
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