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The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer.
Amara CS, Kami Reddy KR, Yuntao Y, Chan YS, Piyarathna DWB, Dobrolecki LE, Shih DJH, Shi Z, Xu J, Huang S, Ellis MJ, Apolo AB, Ballester LY, Gao J, Hansel DE, Lotan Y, Hodges HC, Lerner SP, Creighton CJ, Sreekumar A, Zheng WJ, Msaouel P, Kavuri SM, Putluri N. Amara CS, et al. Among authors: zheng wj. Nat Commun. 2024 Feb 14;15(1):1373. doi: 10.1038/s41467-024-45132-2. Nat Commun. 2024. PMID: 38355560 Free PMC article.
Biomolecular Condensation: A New Phase in Cancer Research.
Chakravarty AK, McGrail DJ, Lozanoski TM, Dunn BS, Shih DJH, Cirillo KM, Cetinkaya SH, Zheng WJ, Mills GB, Yi SS, Jarosz DF, Sahni N. Chakravarty AK, et al. Among authors: zheng wj. Cancer Discov. 2022 Sep 2;12(9):2031-2043. doi: 10.1158/2159-8290.CD-21-1605. Cancer Discov. 2022. PMID: 35852417 Free PMC article. Review.
Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry.
Nguyen TT, Shin DH, Sohoni S, Singh SK, Rivera-Molina Y, Jiang H, Fan X, Gumin J, Lang FF, Alvarez-Breckenridge C, Godoy-Vitorino F, Zhu L, Zheng WJ, Zhai L, Ladomersky E, Lauing KL, Alonso MM, Wainwright DA, Gomez-Manzano C, Fueyo J. Nguyen TT, et al. Among authors: zheng wj. J Immunother Cancer. 2022 Jul;10(7):e004935. doi: 10.1136/jitc-2022-004935. J Immunother Cancer. 2022. PMID: 35902132 Free PMC article.
Ensemble pretrained language models to extract biomedical knowledge from literature.
Li Z, Wei Q, Huang LC, Li J, Hu Y, Chuang YS, He J, Das A, Keloth VK, Yang Y, Diala CS, Roberts KE, Tao C, Jiang X, Zheng WJ, Xu H. Li Z, et al. Among authors: zheng wj. J Am Med Inform Assoc. 2024 Mar 23:ocae061. doi: 10.1093/jamia/ocae061. Online ahead of print. J Am Med Inform Assoc. 2024. PMID: 38520725
495 results