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Drug combination therapy for emerging viral diseases.
Shyr ZA, Cheng YS, Lo DC, Zheng W. Shyr ZA, et al. Among authors: zheng w. Drug Discov Today. 2021 Oct;26(10):2367-2376. doi: 10.1016/j.drudis.2021.05.008. Epub 2021 May 21. Drug Discov Today. 2021. PMID: 34023496 Free PMC article. Review.
Phenotypic screens as a renewed approach for drug discovery.
Zheng W, Thorne N, McKew JC. Zheng W, et al. Drug Discov Today. 2013 Nov;18(21-22):1067-73. doi: 10.1016/j.drudis.2013.07.001. Epub 2013 Jul 9. Drug Discov Today. 2013. PMID: 23850704 Free PMC article. Review.
Drug combination therapy increases successful drug repositioning.
Sun W, Sanderson PE, Zheng W. Sun W, et al. Among authors: zheng w. Drug Discov Today. 2016 Jul;21(7):1189-95. doi: 10.1016/j.drudis.2016.05.015. Epub 2016 May 27. Drug Discov Today. 2016. PMID: 27240777 Free PMC article. Review.
Synergistic drug combination effectively blocks Ebola virus infection.
Sun W, He S, Martínez-Romero C, Kouznetsova J, Tawa G, Xu M, Shinn P, Fisher E, Long Y, Motabar O, Yang S, Sanderson PE, Williamson PR, García-Sastre A, Qiu X, Zheng W. Sun W, et al. Among authors: zheng w. Antiviral Res. 2017 Jan;137:165-172. doi: 10.1016/j.antiviral.2016.11.017. Epub 2016 Nov 24. Antiviral Res. 2017. PMID: 27890675 Free PMC article.
Astrocytes as targets for drug discovery.
Gorshkov K, Aguisanda F, Thorne N, Zheng W. Gorshkov K, et al. Among authors: zheng w. Drug Discov Today. 2018 Mar;23(3):673-680. doi: 10.1016/j.drudis.2018.01.011. Epub 2018 Jan 6. Drug Discov Today. 2018. PMID: 29317338 Free PMC article. Review.
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.
Yang S, Xu M, Lee EM, Gorshkov K, Shiryaev SA, He S, Sun W, Cheng YS, Hu X, Tharappel AM, Lu B, Pinto A, Farhy C, Huang CT, Zhang Z, Zhu W, Wu Y, Zhou Y, Song G, Zhu H, Shamim K, Martínez-Romero C, García-Sastre A, Preston RA, Jayaweera DT, Huang R, Huang W, Xia M, Simeonov A, Ming G, Qiu X, Terskikh AV, Tang H, Song H, Zheng W. Yang S, et al. Among authors: zheng w. Cell Discov. 2018 Jun 5;4:31. doi: 10.1038/s41421-018-0034-1. eCollection 2018. Cell Discov. 2018. PMID: 29872540 Free PMC article.
Advancing precision medicine with personalized drug screening.
Gorshkov K, Chen CZ, Marshall RE, Mihatov N, Choi Y, Nguyen DT, Southall N, Chen KG, Park JK, Zheng W. Gorshkov K, et al. Among authors: zheng w. Drug Discov Today. 2019 Jan;24(1):272-278. doi: 10.1016/j.drudis.2018.08.010. Epub 2018 Aug 17. Drug Discov Today. 2019. PMID: 30125678 Free PMC article. Review.
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