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MYPT1/PP1-Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial-Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes.
Zhang L, Wang L, Hu XB, Hou M, Xiao Y, Xiang JW, Xie J, Chen ZG, Yang TH, Nie Q, Fu JL, Wang Y, Zheng SY, Liu YF, Gan YW, Gao Q, Bai YY, Wang JM, Qi RL, Zou M, Ke Q, Zhu XF, Gong L, Liu Y, Li DW. Zhang L, et al. Among authors: zheng sy. Adv Sci (Weinh). 2022 May;9(14):e2105539. doi: 10.1002/advs.202105539. Epub 2022 Mar 16. Adv Sci (Weinh). 2022. PMID: 35293697 Free PMC article.
The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax.
Nie Q, Chen H, Zou M, Wang L, Hou M, Xiang JW, Luo Z, Gong XD, Fu JL, Wang Y, Zheng SY, Xiao Y, Gan YW, Gao Q, Bai YY, Wang JM, Zhang L, Tang XC, Hu X, Gong L, Liu Y, Li DW. Nie Q, et al. Among authors: zheng sy. Front Cell Dev Biol. 2021 Jun 14;9:660494. doi: 10.3389/fcell.2021.660494. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34195189 Free PMC article.
Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance.
Gong XD, Wang Y, Hu XB, Zheng SY, Fu JL, Nie Q, Wang L, Hou M, Xiang JW, Xiao Y, Gao Q, Bai YY, Liu YZ, Li DW. Gong XD, et al. Among authors: zheng sy. Aging (Albany NY). 2021 Jul 4;13(13):17568-17591. doi: 10.18632/aging.203247. Epub 2021 Jul 4. Aging (Albany NY). 2021. PMID: 34226295 Free PMC article.
PP-1β and PP-2Aα modulate cAMP response element-binding protein (CREB) functions in aging control and stress response through de-regulation of αB-crystallin gene and p300-p53 signaling axis.
Wang L, Zhang L, Gong XD, Fu JL, Gan YW, Hou M, Nie Q, Xiang JW, Xiao Y, Wang Y, Zheng SY, Yang L, Chen H, Xiang MQ, Liu Y, Li DW. Wang L, et al. Among authors: zheng sy. Aging Cell. 2021 Sep;20(9):e13458. doi: 10.1111/acel.13458. Epub 2021 Aug 23. Aging Cell. 2021. PMID: 34425033 Free PMC article.
HSP90β prevents aging-related cataract formation through regulation of the charged multivesicular body protein (CHMP4B) and p53.
Fu JL, Zheng SY, Wang Y, Hu XB, Xiao Y, Wang JM, Zhang L, Wang L, Nie Q, Hou M, Bai YY, Gan YW, Liang XM, Xie LL, Li DW. Fu JL, et al. Among authors: zheng sy. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2221522120. doi: 10.1073/pnas.2221522120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487085 Free PMC article.
298 results