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DAXX-ATRX regulation of p53 chromatin binding and DNA damage response.
Gulve N, Su C, Deng Z, Soldan SS, Vladimirova O, Wickramasinghe J, Zheng H, Kossenkov AV, Lieberman PM. Gulve N, et al. Among authors: zheng h. Nat Commun. 2022 Aug 26;13(1):5033. doi: 10.1038/s41467-022-32680-8. Nat Commun. 2022. PMID: 36028493 Free PMC article.
ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization.
Li F, Deng Z, Zhang L, Wu C, Jin Y, Hwang I, Vladimirova O, Xu L, Yang L, Lu B, Dheekollu J, Li JY, Feng H, Hu J, Vakoc CR, Ying H, Paik J, Lieberman PM, Zheng H. Li F, et al. Among authors: zheng h. EMBO J. 2019 Oct 1;38(19):e96659. doi: 10.15252/embj.201796659. Epub 2019 Aug 27. EMBO J. 2019. PMID: 31454099 Free PMC article.
ZNF365 promotes stability of fragile sites and telomeres.
Zhang Y, Shin SJ, Liu D, Ivanova E, Foerster F, Ying H, Zheng H, Xiao Y, Chen Z, Protopopov A, Depinho RA, Paik JH. Zhang Y, et al. Among authors: zheng h. Cancer Discov. 2013 Jul;3(7):798-811. doi: 10.1158/2159-8290.CD-12-0536. Epub 2013 Jun 17. Cancer Discov. 2013. PMID: 23776040 Free PMC article.
CIC is a critical regulator of neuronal differentiation.
Hwang I, Pan H, Yao J, Elemento O, Zheng H, Paik J. Hwang I, et al. Among authors: zheng h. JCI Insight. 2020 May 7;5(9):e135826. doi: 10.1172/jci.insight.135826. JCI Insight. 2020. PMID: 32229723 Free PMC article.
A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.
Jang JY, Hwang I, Pan H, Yao J, Alinari L, Imada E, Zanettini C, Kluk MJ, Wang Y, Lee Y, Lin HV, Huang X, Di Liberto M, Chen Z, Ballman KV, Cantley LC, Marchionni L, Inghirami G, Elemento O, Baiocchi RA, Chen-Kiang S, Belvedere S, Zheng H, Paik J. Jang JY, et al. Among authors: zheng h. J Clin Invest. 2022 Dec 15;132(24):e160767. doi: 10.1172/JCI160767. J Clin Invest. 2022. PMID: 36282572 Free PMC article.
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA. Zheng H, et al. Nature. 2008 Oct 23;455(7216):1129-33. doi: 10.1038/nature07443. Nature. 2008. PMID: 18948956 Free PMC article.
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