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2004 2
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2019 6
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46 results

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Page 1
Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate.
Wang R, Suzuki S, Guest JD, Heller B, Almeda M, Andrianov AK, Marin A, Mariuzza RA, Keck ZY, Foung SKH, Yunus AS, Pierce BG, Toth EA, Ploss A, Fuerst TR. Wang R, et al. Among authors: keck zy. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2112008119. doi: 10.1073/pnas.2112008119. Epub 2022 Mar 9. Proc Natl Acad Sci U S A. 2022. PMID: 35263223 Free PMC article.
Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer.
Guest JD, Wang R, Elkholy KH, Chagas A, Chao KL, Cleveland TE 4th, Kim YC, Keck ZY, Marin A, Yunus AS, Mariuzza RA, Andrianov AK, Toth EA, Foung SKH, Pierce BG, Fuerst TR. Guest JD, et al. Among authors: keck zy. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2015149118. doi: 10.1073/pnas.2015149118. Proc Natl Acad Sci U S A. 2021. PMID: 33431677 Free PMC article.
Crystal Structure of a Bivalent Antibody Fab Fragment.
Shahid S, Gao M, Travis Gallagher D, Pozharski E, Brinson RG, Keck ZY, Foung SKH, Fuerst TR, Mariuzza RA. Shahid S, et al. Among authors: keck zy. J Mol Biol. 2021 Jan 22;433(2):166714. doi: 10.1016/j.jmb.2020.11.013. Epub 2020 Nov 19. J Mol Biol. 2021. PMID: 33220264
Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization.
Pierce BG, Keck ZY, Wang R, Lau P, Garagusi K, Elkholy K, Toth EA, Urbanowicz RA, Guest JD, Agnihotri P, Kerzic MC, Marin A, Andrianov AK, Ball JK, Mariuzza RA, Fuerst TR, Foung SKH. Pierce BG, et al. Among authors: keck zy. J Virol. 2020 Oct 27;94(22):e00704-20. doi: 10.1128/JVI.00704-20. Print 2020 Oct 27. J Virol. 2020. PMID: 32878891 Free PMC article.
An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Tzarum N, Giang E, Kadam RU, Chen F, Nagy K, Augestad EH, Velázquez-Moctezuma R, Keck ZY, Hua Y, Stanfield RL, Dreux M, Prentoe J, Foung SKH, Bukh J, Wilson IA, Law M. Tzarum N, et al. Among authors: keck zy. Sci Adv. 2020 Jul 24;6(30):eabb5642. doi: 10.1126/sciadv.abb5642. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32754640 Free PMC article.
Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design.
Keck ZY, Pierce BG, Lau P, Lu J, Wang Y, Underwood A, Bull RA, Prentoe J, Velázquez-Moctezuma R, Walker MR, Luciani F, Guest JD, Fauvelle C, Baumert TF, Bukh J, Lloyd AR, Foung SKH. Keck ZY, et al. PLoS Pathog. 2019 May 17;15(5):e1007772. doi: 10.1371/journal.ppat.1007772. eCollection 2019 May. PLoS Pathog. 2019. PMID: 31100098 Free PMC article.
Learning from a clinical cohort for HCV vaccine development.
Wrensch F, Keck ZY, Foung SKH, Baumert TF. Wrensch F, et al. Among authors: keck zy. J Hepatol. 2019 Jul;71(1):9-11. doi: 10.1016/j.jhep.2019.03.030. Epub 2019 Apr 13. J Hepatol. 2019. PMID: 30992137 Free PMC article. No abstract available.
Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells.
Urbanowicz RA, Wang R, Schiel JE, Keck ZY, Kerzic MC, Lau P, Rangarajan S, Garagusi KJ, Tan L, Guest JD, Ball JK, Pierce BG, Mariuzza RA, Foung SKH, Fuerst TR. Urbanowicz RA, et al. Among authors: keck zy. J Virol. 2019 Mar 21;93(7):e01403-18. doi: 10.1128/JVI.01403-18. Print 2019 Apr 1. J Virol. 2019. PMID: 30651366 Free PMC article.
In vivo combination of human anti-envelope glycoprotein E2 and -Claudin-1 monoclonal antibodies for prevention of hepatitis C virus infection.
Mailly L, Wrensch F, Heydmann L, Fauvelle C, Brignon N, Zeisel MB, Pessaux P, Keck ZY, Schuster C, Fuerst TR, Foung SKH, Baumert TF. Mailly L, et al. Among authors: keck zy. Antiviral Res. 2019 Feb;162:136-141. doi: 10.1016/j.antiviral.2018.12.018. Epub 2018 Dec 30. Antiviral Res. 2019. PMID: 30599173 Free PMC article.
46 results