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A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging.
Pun FW, Leung GHD, Leung HW, Rice J, Schmauck-Medina T, Lautrup S, Long X, Liu BHM, Wong CW, Ozerov IV, Aliper A, Ren F, Rosenberg AJ, Agrawal N, Izumchenko E, Fang EF, Zhavoronkov A. Pun FW, et al. Among authors: zhavoronkov a. Aging Cell. 2023 Dec;22(12):e14017. doi: 10.1111/acel.14017. Epub 2023 Oct 27. Aging Cell. 2023. PMID: 37888486 Free PMC article.
Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease.
Moskalev A, Chernyagina E, de Magalhães JP, Barardo D, Thoppil H, Shaposhnikov M, Budovsky A, Fraifeld VE, Garazha A, Tsvetkov V, Bronovitsky E, Bogomolov V, Scerbacov A, Kuryan O, Gurinovich R, Jellen LC, Kennedy B, Mamoshina P, Dobrovolskaya E, Aliper A, Kaminsky D, Zhavoronkov A. Moskalev A, et al. Among authors: zhavoronkov a. Aging (Albany NY). 2015 Sep;7(9):616-28. doi: 10.18632/aging.100799. Aging (Albany NY). 2015. PMID: 26342919 Free PMC article.
Common pathway signature in lung and liver fibrosis.
Makarev E, Izumchenko E, Aihara F, Wysocki PT, Zhu Q, Buzdin A, Sidransky D, Zhavoronkov A, Atala A. Makarev E, et al. Among authors: zhavoronkov a. Cell Cycle. 2016 Jul 2;15(13):1667-73. doi: 10.1080/15384101.2016.1152435. Epub 2016 Jun 7. Cell Cycle. 2016. PMID: 27267766 Free PMC article.
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development.
Ozerov IV, Lezhnina KV, Izumchenko E, Artemov AV, Medintsev S, Vanhaelen Q, Aliper A, Vijg J, Osipov AN, Labat I, West MD, Buzdin A, Cantor CR, Nikolsky Y, Borisov N, Irincheeva I, Khokhlovich E, Sidransky D, Camargo ML, Zhavoronkov A. Ozerov IV, et al. Among authors: zhavoronkov a. Nat Commun. 2016 Nov 16;7:13427. doi: 10.1038/ncomms13427. Nat Commun. 2016. PMID: 27848968 Free PMC article.
Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells.
Pustovalova M, Grekhova A, Astrelina Т, Nikitina V, Dobrovolskaya E, Suchkova Y, Kobzeva I, Usupzhanova D, Vorobyeva N, Samoylov A, Bushmanov A, Ozerov IV, Zhavoronkov A, Leonov S, Klokov D, Osipov AN. Pustovalova M, et al. Among authors: zhavoronkov a. Aging (Albany NY). 2016 Dec 11;8(12):3498-3506. doi: 10.18632/aging.101142. Aging (Albany NY). 2016. PMID: 27959319 Free PMC article.
In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia.
Makarev E, Schubert AD, Kanherkar RR, London N, Teka M, Ozerov I, Lezhnina K, Bedi A, Ravi R, Mehra R, Hoque MO, Sloma I, Gaykalova DA, Csoka AB, Sidransky D, Zhavoronkov A, Izumchenko E. Makarev E, et al. Among authors: zhavoronkov a. Cell Death Discov. 2017 May 22;3:17022. doi: 10.1038/cddiscovery.2017.22. eCollection 2017. Cell Death Discov. 2017. PMID: 28580171 Free PMC article.
An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical foam in men with androgenetic alopecia.
Stamatas GN, Wu J, Pappas A, Mirmirani P, McCormick TS, Cooper KD, Consolo M, Schastnaya J, Ozerov IV, Aliper A, Zhavoronkov A. Stamatas GN, et al. Among authors: zhavoronkov a. Cell Cycle. 2017;16(17):1578-1584. doi: 10.1080/15384101.2017.1327492. Epub 2017 Jun 8. Cell Cycle. 2017. PMID: 28594262 Free PMC article.
256 results