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Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle.
Feng J, Zhao Y, Xie Z, Zang K, Sviben S, Hu X, Fitzpatrick JAJ, Wen L, Liu Y, Wang T, Lawson K, Liu Q, Yan Y, Dong X, Han L, Wu GF, Kim BS, Hu H. Feng J, et al. Among authors: zhao y. Sci Transl Med. 2022 Jul 13;14(653):eabn4819. doi: 10.1126/scitranslmed.abn4819. Epub 2022 Jul 13. Sci Transl Med. 2022. PMID: 35857641 Free PMC article.
Cryo-EM structure of a proton-activated chloride channel TMEM206.
Deng Z, Zhao Y, Feng J, Zhang J, Zhao H, Rau MJ, Fitzpatrick JAJ, Hu H, Yuan P. Deng Z, et al. Among authors: zhao h, zhao y. Sci Adv. 2021 Feb 24;7(9):eabe5983. doi: 10.1126/sciadv.abe5983. Print 2021 Feb. Sci Adv. 2021. PMID: 33627432 Free PMC article.
Mechanisms of Broad-Band UVB Irradiation‒Induced Itch in Mice.
Cao L, Yue X, Zhao Y, Du L, Xie Z, Yuan Y, Zhang S, Li F, Feng J, Hu H. Cao L, et al. Among authors: zhao y. J Invest Dermatol. 2021 Oct;141(10):2499-2508.e3. doi: 10.1016/j.jid.2021.03.015. Epub 2021 Apr 1. J Invest Dermatol. 2021. PMID: 33812858 Free PMC article.
IL-33 signaling in sensory neurons promotes dry skin itch.
Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. Trier AM, et al. Among authors: zhao y. J Allergy Clin Immunol. 2022 Apr;149(4):1473-1480.e6. doi: 10.1016/j.jaci.2021.09.014. Epub 2021 Sep 21. J Allergy Clin Immunol. 2022. PMID: 34560104 Free PMC article.
Mechanosensitive TRPV4 is required for crystal-induced inflammation.
Lan Z, Chen L, Feng J, Xie Z, Liu Z, Wang F, Liu P, Yue X, Du L, Zhao Y, Yang P, Luo J, Zhu Z, Hu X, Cao L, Lu P, Sah R, Lavine K, Kim B, Hu H. Lan Z, et al. Among authors: zhao y. Ann Rheum Dis. 2021 Dec;80(12):1604-1614. doi: 10.1136/annrheumdis-2021-220295. Epub 2021 Oct 18. Ann Rheum Dis. 2021. PMID: 34663597 Free PMC article.
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