Zhao XZ - Search Results

1

Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.

Li M, Oliveira Passos D, Shan Z, Smith SJ, Sun Q, Biswas A, Choudhuri I, Strutzenberg TS, Haldane A, Deng N, Li Z, Zhao XZ, Briganti L, Kvaratskhelia M, Burke TR Jr, Levy RM, Hughes SH, Craigie R, Lyumkis D. Li M, et al. Among authors: zhao xz. Sci Adv. 2023 Jul 21;9(29):eadg5953. doi: 10.1126/sciadv.adg5953. Epub 2023 Jul 21. Sci Adv. 2023. PMID: 37478179 Free article.

2

Biotinylated biphenyl ketone-containing 2,4-dioxobutanoic acids designed as HIV-1 integrase photoaffinity ligands.

Zhao XZ, Semenova EA, Liao C, Nicklaus M, Pommier Y, Burke TR Jr. Zhao XZ, et al. Bioorg Med Chem. 2006 Dec 1;14(23):7816-25. doi: 10.1016/j.bmc.2006.07.064. Epub 2006 Sep 26. Bioorg Med Chem. 2006. PMID: 16908168

3

2,3-dihydro-6,7-dihydroxy-1H-isoindol-1-one-based HIV-1 integrase inhibitors.

Zhao XZ, Semenova EA, Vu BC, Maddali K, Marchand C, Hughes SH, Pommier Y, Burke TR Jr. Zhao XZ, et al. J Med Chem. 2008 Jan 24;51(2):251-9. doi: 10.1021/jm070715d. Epub 2007 Dec 21. J Med Chem. 2008. PMID: 18095643

4

Examination of halogen substituent effects on HIV-1 integrase inhibitors derived from 2,3-dihydro-6,7-dihydroxy-1H-isoindol-1-ones and 4,5-dihydroxy-1H-isoindole-1,3(2H)-diones.

Zhao XZ, Maddali K, Vu BC, Marchand C, Hughes SH, Pommier Y, Burke TR Jr. Zhao XZ, et al. Bioorg Med Chem Lett. 2009 May 15;19(10):2714-7. doi: 10.1016/j.bmcl.2009.03.122. Epub 2009 Mar 28. Bioorg Med Chem Lett. 2009. PMID: 19364649 Free PMC article.

5

Diketoacid-genre HIV-1 integrase inhibitors containing enantiomeric arylamide functionality.

Zhao XZ, Maddali K, Marchand C, Pommier Y, Burke TR Jr. Zhao XZ, et al. Bioorg Med Chem. 2009 Jul 15;17(14):5318-24. doi: 10.1016/j.bmc.2009.05.008. Epub 2009 May 8. Bioorg Med Chem. 2009. PMID: 19527935 Free PMC article.

6

Comparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solution.

Andrake MD, Ramcharan J, Merkel G, Zhao XZ, Burke TR Jr, Skalka AM. Andrake MD, et al. Among authors: zhao xz. AIDS Res Ther. 2009 Jun 29;6:14. doi: 10.1186/1742-6405-6-14. AIDS Res Ther. 2009. PMID: 19563676 Free PMC article.

7

Crystallographic and functional analysis of the ESCRT-I /HIV-1 Gag PTAP interaction.

Im YJ, Kuo L, Ren X, Burgos PV, Zhao XZ, Liu F, Burke TR Jr, Bonifacino JS, Freed EO, Hurley JH. Im YJ, et al. Among authors: zhao xz. Structure. 2010 Nov 10;18(11):1536-47. doi: 10.1016/j.str.2010.08.010. Structure. 2010. PMID: 21070952 Free PMC article.

8

Development of tricyclic hydroxy-1H-pyrrolopyridine-trione containing HIV-1 integrase inhibitors.

Zhao XZ, Maddali K, Metifiot M, Smith SJ, Vu BC, Marchand C, Hughes SH, Pommier Y, Burke TR Jr. Zhao XZ, et al. Bioorg Med Chem Lett. 2011 May 15;21(10):2986-90. doi: 10.1016/j.bmcl.2011.03.047. Epub 2011 Mar 21. Bioorg Med Chem Lett. 2011. PMID: 21493066 Free PMC article.

9

MK-0536 inhibits HIV-1 integrases resistant to raltegravir.

Métifiot M, Johnson B, Smith S, Zhao XZ, Marchand C, Burke T, Hughes S, Pommier Y. Métifiot M, et al. Among authors: zhao xz. Antimicrob Agents Chemother. 2011 Nov;55(11):5127-33. doi: 10.1128/AAC.05288-11. Epub 2011 Aug 29. Antimicrob Agents Chemother. 2011. PMID: 21876054 Free PMC article.

10

Bicyclic hydroxy-1H-pyrrolopyridine-trione containing HIV-1 integrase inhibitors.

Zhao XZ, Maddali K, Metifiot M, Smith SJ, Vu BC, Marchand C, Hughes SH, Pommier Y, Burke TR Jr. Zhao XZ, et al. Chem Biol Drug Des. 2012 Feb;79(2):157-65. doi: 10.1111/j.1747-0285.2011.01270.x. Epub 2011 Dec 22. Chem Biol Drug Des. 2012. PMID: 22107736 Free PMC article.

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