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SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling.
Li F, Li J, Wang PH, Yang N, Huang J, Ou J, Xu T, Zhao X, Liu T, Huang X, Wang Q, Li M, Yang L, Lin Y, Cai Y, Chen H, Zhang Q. Li F, et al. Among authors: zhao x. Biochim Biophys Acta Mol Basis Dis. 2021 Dec 1;1867(12):166260. doi: 10.1016/j.bbadis.2021.166260. Epub 2021 Aug 27. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 34461258 Free PMC article.
c-Mpl-del, a c-Mpl alternative splicing isoform, promotes AMKL progression and chemoresistance.
Li F, Xiong Y, Yang M, Chen P, Zhang J, Wang Q, Xu M, Wang Y, He Z, Zhao X, Huang J, Gu X, Zhang L, Sun R, Sun X, Li J, Ou J, Xu T, Huang X, Cao Y, Xu XR, Karakas D, Li J, Ni H, Zhang Q. Li F, et al. Among authors: zhao x. Cell Death Dis. 2022 Oct 13;13(10):869. doi: 10.1038/s41419-022-05315-5. Cell Death Dis. 2022. PMID: 36229456 Free PMC article.
A positive feedback loop between Periostin and TGFβ1 induces and maintains the stemness of hepatocellular carcinoma cells via AP-2α activation.
Chen G, Wang Y, Zhao X, Xie XZ, Zhao JG, Deng T, Chen ZY, Chen HB, Tong YF, Yang Z, Ding XW, Guo PY, Yu HT, Wu LJ, Zhang SN, Zhu QD, Li JJ, Shan YF, Yu FX, Yu ZP, Xia JL. Chen G, et al. Among authors: zhao x, zhao jg. J Exp Clin Cancer Res. 2021 Jun 30;40(1):218. doi: 10.1186/s13046-021-02011-8. J Exp Clin Cancer Res. 2021. PMID: 34193219 Free PMC article. Clinical Trial.
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