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Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-beta promoter.
Zhao W, Wang L, Zhang M, Wang P, Zhang L, Yuan C, Qi J, Qiao Y, Kuo PC, Gao C. Zhao W, et al. J Biol Chem. 2011 Feb 18;286(7):5519-28. doi: 10.1074/jbc.M110.149823. Epub 2010 Dec 10. J Biol Chem. 2011. PMID: 21148557 Free PMC article.
Redox homeostasis maintained by GPX4 facilitates STING activation.
Jia M, Qin D, Zhao C, Chai L, Yu Z, Wang W, Tong L, Lv L, Wang Y, Rehwinkel J, Yu J, Zhao W. Jia M, et al. Among authors: zhao w, zhao c. Nat Immunol. 2020 Jul;21(7):727-735. doi: 10.1038/s41590-020-0699-0. Epub 2020 Jun 15. Nat Immunol. 2020. PMID: 32541831
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