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DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Ren W, Fan H, Grimm SA, Kim JJ, Li L, Guo Y, Petell CJ, Tan XF, Zhang ZM, Coan JP, Yin J, Kim DI, Gao L, Cai L, Khudaverdyan N, Çetin B, Patel DJ, Wang Y, Cui Q, Strahl BD, Gozani O, Miller KM, O'Leary SE, Wade PA, Wang GG, Song J. Ren W, et al. Among authors: zhang zm. Nat Commun. 2021 May 3;12(1):2490. doi: 10.1038/s41467-021-22665-4. Nat Commun. 2021. PMID: 33941775 Free PMC article.
Crystal Structure of Human DNA Methyltransferase 1.
Zhang ZM, Liu S, Lin K, Luo Y, Perry JJ, Wang Y, Song J. Zhang ZM, et al. J Mol Biol. 2015 Jul 31;427(15):2520-2531. doi: 10.1016/j.jmb.2015.06.001. Epub 2015 Jun 10. J Mol Biol. 2015. PMID: 26070743 Free PMC article.
Structural basis for DNMT3A-mediated de novo DNA methylation.
Zhang ZM, Lu R, Wang P, Yu Y, Chen D, Gao L, Liu S, Ji D, Rothbart SB, Wang Y, Wang GG, Song J. Zhang ZM, et al. Nature. 2018 Feb 15;554(7692):387-391. doi: 10.1038/nature25477. Epub 2018 Feb 7. Nature. 2018. PMID: 29414941 Free PMC article.
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Gao L, Emperle M, Guo Y, Grimm SA, Ren W, Adam S, Uryu H, Zhang ZM, Chen D, Yin J, Dukatz M, Anteneh H, Jurkowska RZ, Lu J, Wang Y, Bashtrykov P, Wade PA, Wang GG, Jeltsch A, Song J. Gao L, et al. Among authors: zhang zm. Nat Commun. 2020 Jul 3;11(1):3355. doi: 10.1038/s41467-020-17109-4. Nat Commun. 2020. PMID: 32620778 Free PMC article.
Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Ren W, Fan H, Grimm SA, Guo Y, Kim JJ, Yin J, Li L, Petell CJ, Tan XF, Zhang ZM, Coan JP, Gao L, Cai L, Detrick B, Çetin B, Cui Q, Strahl BD, Gozani O, Wang Y, Miller KM, O'Leary SE, Wade PA, Patel DJ, Wang GG, Song J. Ren W, et al. Among authors: zhang zm. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18439-18447. doi: 10.1073/pnas.2009316117. Epub 2020 Jul 16. Proc Natl Acad Sci U S A. 2020. PMID: 32675241 Free PMC article.
1,059 results