Zhang Z - Search Results

1

An updated patent review of Mcl-1 inhibitors (2020-2022).

Liu J, Yin F, Wang Z, Song T, Zhang Z. Liu J, et al. Among authors: zhang z. Expert Opin Ther Pat. 2023 Jan-Jun;33(5):371-383. doi: 10.1080/13543776.2023.2219394. Epub 2023 Jun 14. Expert Opin Ther Pat. 2023. PMID: 37293764 Review.

2

Potency and property of DNA conformational damage determine ATM activation: two new DNA topological probes.

Zhang Z, Wang Y, Zhang J, Song T, Qian X. Zhang Z, et al. Among authors: zhang j. Cell Biochem Funct. 2008 Oct;26(7):808-12. doi: 10.1002/cbf.1510. Cell Biochem Funct. 2008. PMID: 18788070

3

Tanshinone IIA interacts with DNA by minor groove-binding.

Zhang Z, Zhang J, Jin L, Song T, Wu G, Gao J. Zhang Z, et al. Among authors: zhang j. Biol Pharm Bull. 2008 Dec;31(12):2342-5. doi: 10.1248/bpb.31.2342. Biol Pharm Bull. 2008. PMID: 19043224 Free article.

4

DNA double helix unwinding triggers transcription block-dependent apoptosis: a semiquantitative probe of the response of ATM, RNAPII, and p53 to two DNA intercalators.

Zhang Z, Wang Y, Song T, Gao J, Wu G, Zhang J, Qian X. Zhang Z, et al. Among authors: zhang j. Chem Res Toxicol. 2009 Mar 16;22(3):483-91. doi: 10.1021/tx800288v. Chem Res Toxicol. 2009. PMID: 19182866

5

Tanshinone IIA triggers p53 responses and apoptosis by RNA polymerase II upon DNA minor groove binding.

Zhang Z, Gao J, Wang Y, Song T, Zhang J, Wu G, Zhang T, Du G. Zhang Z, et al. Among authors: zhang t, zhang j. Biochem Pharmacol. 2009 Nov 15;78(10):1316-22. doi: 10.1016/j.bcp.2009.06.110. Epub 2009 Jul 8. Biochem Pharmacol. 2009. PMID: 19591811

6

A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1.

Zhang Z, Song T, Zhang T, Gao J, Wu G, An L, Du G. Zhang Z, et al. Among authors: zhang t. Int J Cancer. 2011 Apr 1;128(7):1724-35. doi: 10.1002/ijc.25484. Epub 2010 May 25. Int J Cancer. 2011. PMID: 20503275 Free article.

7

Inclusion complex of a Bcl-2 inhibitor with cyclodextrin: characterization, cellular accumulation, and in vivo antitumor activity.

Zhang Z, Wu G, Gao J, Song T. Zhang Z, et al. Mol Pharm. 2010 Aug 2;7(4):1348-54. doi: 10.1021/mp100081x. Mol Pharm. 2010. PMID: 20550194

8

3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile (S1) based molecules as potent, dual inhibitors of B-cell lymphoma 2 (Bcl-2) and myeloid cell leukemia sequence 1 (Mcl-1): structure-based design and structure-activity relationship studies.

Zhang Z, Wu G, Xie F, Song T, Chang X. Zhang Z, et al. J Med Chem. 2011 Feb 24;54(4):1101-5. doi: 10.1021/jm101181u. Epub 2011 Jan 14. J Med Chem. 2011. PMID: 21235240

9

Probing the difference between BH3 groove of Mcl-1 and Bcl-2 protein: Implications for dual inhibitors design.

Zhang Z, Yang H, Wu G, Li Z, Song T, Li XQ. Zhang Z, et al. Eur J Med Chem. 2011 Sep;46(9):3909-16. doi: 10.1016/j.ejmech.2011.05.062. Epub 2011 May 31. Eur J Med Chem. 2011. PMID: 21684048

10

S1, a novel pan-BH3 mimetic, induces apoptosis in Mcl-1-overexpressing cells through Bak.

Song T, Chang X, Zhang Z, Liu Y, Shen X. Song T, et al. Among authors: zhang z. J Pharmacol Sci. 2012;119(4):330-40. doi: 10.1254/jphs.12103fp. Epub 2012 Jul 12. J Pharmacol Sci. 2012. PMID: 22814102 Free article.

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