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A2B adenosine receptor-mediated induction of IL-6 promotes CKD.
Dai Y, Zhang W, Wen J, Zhang Y, Kellems RE, Xia Y. Dai Y, et al. Among authors: zhang w, zhang y. J Am Soc Nephrol. 2011 May;22(5):890-901. doi: 10.1681/ASN.2010080890. Epub 2011 Apr 21. J Am Soc Nephrol. 2011. PMID: 21511827 Free PMC article.
Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia.
Sun K, Zhang Y, D'Alessandro A, Nemkov T, Song A, Wu H, Liu H, Adebiyi M, Huang A, Wen YE, Bogdanov MV, Vila A, O'Brien J, Kellems RE, Dowhan W, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Safo M, Hansen KC, Roach RC, Xia Y. Sun K, et al. Among authors: zhang y. Nat Commun. 2016 Jul 15;7:12086. doi: 10.1038/ncomms12086. Nat Commun. 2016. PMID: 27417539 Free PMC article.
Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming.
Qiang Q, Manalo JM, Sun H, Zhang Y, Song A, Wen AQ, Wen YE, Chen C, Liu H, Cui Y, Nemkov T, Reisz JA, Edwards Iii G, Perreira FA, Kellems RE, Soto C, D'Alessandro A, Xia Y. Qiang Q, et al. Among authors: zhang y. PLoS Biol. 2021 Jun 17;19(6):e3001239. doi: 10.1371/journal.pbio.3001239. eCollection 2021 Jun. PLoS Biol. 2021. PMID: 34138843 Free PMC article.
Detrimental effects of adenosine signaling in sickle cell disease.
Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Zhang Y, et al. Among authors: zhang w. Nat Med. 2011 Jan;17(1):79-86. doi: 10.1038/nm.2280. Epub 2010 Dec 19. Nat Med. 2011. PMID: 21170046 Free PMC article.
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y. Zhang W, et al. Among authors: zhang y. Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166. Epub 2013 Apr 12. Circ Res. 2013. PMID: 23584256 Free PMC article.
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