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Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N. Sun H, et al. Among authors: zhang t, zhang z, zhang j, zhang y. Protein Cell. 2024 Feb 1;15(2):121-134. doi: 10.1093/procel/pwad040. Protein Cell. 2024. PMID: 37470320 Free PMC article.
HBV life cycle is restricted in mouse hepatocytes expressing human NTCP.
Li H, Zhuang Q, Wang Y, Zhang T, Zhao J, Zhang Y, Zhang J, Lin Y, Yuan Q, Xia N, Han J. Li H, et al. Among authors: zhang t, zhang j, zhang y. Cell Mol Immunol. 2014 Mar;11(2):175-83. doi: 10.1038/cmi.2013.66. Epub 2014 Feb 10. Cell Mol Immunol. 2014. PMID: 24509445 Free PMC article.
Prolonged suppression of HBV in mice by a novel antibody that targets a unique epitope on hepatitis B surface antigen.
Zhang TY, Yuan Q, Zhao JH, Zhang YL, Yuan LZ, Lan Y, Lo YC, Sun CP, Wu CR, Zhang JF, Zhang Y, Cao JL, Guo XR, Liu X, Mo XB, Luo WX, Cheng T, Chen YX, Tao MH, Shih JW, Zhao QJ, Zhang J, Chen PJ, Yuan YA, Xia NS. Zhang TY, et al. Among authors: zhang jf, zhang j, zhang yl, zhang y. Gut. 2016 Apr;65(4):658-71. doi: 10.1136/gutjnl-2014-308964. Epub 2015 Sep 30. Gut. 2016. PMID: 26423112
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