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TLR7 gain-of-function genetic variation causes human lupus.
Brown GJ, Cañete PF, Wang H, Medhavy A, Bones J, Roco JA, He Y, Qin Y, Cappello J, Ellyard JI, Bassett K, Shen Q, Burgio G, Zhang Y, Turnbull C, Meng X, Wu P, Cho E, Miosge LA, Andrews TD, Field MA, Tvorogov D, Lopez AF, Babon JJ, López CA, Gónzalez-Murillo Á, Garulo DC, Pascual V, Levy T, Mallack EJ, Calame DG, Lotze T, Lupski JR, Ding H, Ullah TR, Walters GD, Koina ME, Cook MC, Shen N, de Lucas Collantes C, Corry B, Gantier MP, Athanasopoulos V, Vinuesa CG. Brown GJ, et al. Among authors: zhang y. Nature. 2022 May;605(7909):349-356. doi: 10.1038/s41586-022-04642-z. Epub 2022 Apr 27. Nature. 2022. PMID: 35477763 Free PMC article.
A protocol to evaluate immunoglobulin deposits in mouse glomeruli.
Nambadan SB, Stanley M, Zhang Y, Athanasopoulos V, Jiang SH. Nambadan SB, et al. Among authors: zhang y. STAR Protoc. 2022 May 11;3(2):101375. doi: 10.1016/j.xpro.2022.101375. eCollection 2022 Jun 17. STAR Protoc. 2022. PMID: 35600919 Free PMC article.
De Novo PACSIN1 Gene Variant Found in Childhood Lupus and a Role for PACSIN1/TRAF4 Complex in Toll-like Receptor 7 Activation.
Xie C, Zhou H, Athanasopoulos V, Shen Q, Zhang Y, Meng X, Burgio G, Arsov T, Lungu AC, Zhang P, Qin Y, Ma J, Wu X, Jiang X, Ding H, Meng Y, Shen N, He Y, Vinuesa CG. Xie C, et al. Among authors: zhang p, zhang y. Arthritis Rheumatol. 2023 Jun;75(6):1058-1071. doi: 10.1002/art.42416. Epub 2023 Mar 30. Arthritis Rheumatol. 2023. PMID: 36622335
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity.
Zhang Y, Morris R, Brown GJ, Lorenzo AMD, Meng X, Kershaw NJ, Kiridena P, Burgio G, Gross S, Cappello JY, Shen Q, Wang H, Turnbull C, Lea-Henry T, Stanley M, Yu Z, Ballard FD, Chuah A, Lee JC, Hatch AM, Enders A, Masters SL, Headley AP, Trnka P, Mallon D, Fletcher JT, Walters GD, Šestan M, Jelušić M, Cook MC, Athanasopoulos V, Fulcher DA, Babon JJ, Vinuesa CG, Ellyard JI. Zhang Y, et al. J Exp Med. 2024 Apr 1;221(4):e20221080. doi: 10.1084/jem.20221080. Epub 2024 Feb 28. J Exp Med. 2024. PMID: 38417019
Identifying the Crucial Biomarker of MASH-Related HCC.
Zhou H, Zhang Y, Shen Y, Chen S, Yang Z, Wang Z, Qin X, Zhu C. Zhou H, et al. Among authors: zhang y. Comb Chem High Throughput Screen. 2024 May 9. doi: 10.2174/0113862073287250240424073108. Online ahead of print. Comb Chem High Throughput Screen. 2024. PMID: 38726780
Antimicrobial therapy based on self-assembling peptides.
Wang Y, Zhang Y, Su R, Wang Y, Qi W. Wang Y, et al. Among authors: zhang y. J Mater Chem B. 2024 May 10. doi: 10.1039/d4tb00260a. Online ahead of print. J Mater Chem B. 2024. PMID: 38726712 Review.
Spexin Diminishes Atrial Fibrillation Vulnerability by Acting on Galanin Receptor 2.
Li D, Liu Y, Li C, Zhou Z, Gao K, Ba H, Yang J, Xue G, Yin D, Zhao X, Shen K, Zhang L, Li J, Li C, Song J, Zhao L, Pei Y, Xuan L, Zhang Y, Lu Y, Zhang ZR, Yang B, Li Y, Pan Z. Li D, et al. Among authors: zhang y. Circulation. 2024 May 10. doi: 10.1161/CIRCULATIONAHA.123.067517. Online ahead of print. Circulation. 2024. PMID: 38726666
A multicenter, randomized, open-label, phase 2 clinical study of telitacicept in adult patients with generalized myasthenia gravis.
Yin J, Zhao M, Xu X, Zhang M, Xu Z, Li Z, Qin X, Li Z, Zhao C, Zhou H, Ma Y, Cao W, Wang G, Lin Y, Zhang J, Zhang X, Cai H, Qian W, Wang Y, Zhang X, Liu G, Wang J, Qiu W, Min L, Li J, Deng H, Chu L, Zhang Y, Fang J. Yin J, et al. Among authors: zhang y. Eur J Neurol. 2024 May 10:e16322. doi: 10.1111/ene.16322. Online ahead of print. Eur J Neurol. 2024. PMID: 38726639
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