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Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors.
Zhao F, Zhou Q, Cong Z, Hang K, Zou X, Zhang C, Chen Y, Dai A, Liang A, Ming Q, Wang M, Chen LN, Xu P, Chang R, Feng W, Xia T, Zhang Y, Wu B, Yang D, Zhao L, Xu HE, Wang MW. Zhao F, et al. Among authors: zhang c, zhang y. Nat Commun. 2022 Feb 25;13(1):1057. doi: 10.1038/s41467-022-28683-0. Nat Commun. 2022. PMID: 35217653 Free PMC article.
Structural insights into the activation of metabotropic glutamate receptors.
Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laeremans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK. Koehl A, et al. Among authors: zhang y. Nature. 2019 Feb;566(7742):79-84. doi: 10.1038/s41586-019-0881-4. Epub 2019 Jan 23. Nature. 2019. PMID: 30675062 Free PMC article.
Structure and dynamics of the active human parathyroid hormone receptor-1.
Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y. Zhao LH, et al. Among authors: zhang y. Science. 2019 Apr 12;364(6436):148-153. doi: 10.1126/science.aav7942. Science. 2019. PMID: 30975883 Free PMC article.
Conformational transitions of a neurotensin receptor 1-Gi1 complex.
Kato HE, Zhang Y, Hu H, Suomivuori CM, Kadji FMN, Aoki J, Krishna Kumar K, Fonseca R, Hilger D, Huang W, Latorraca NR, Inoue A, Dror RO, Kobilka BK, Skiniotis G. Kato HE, et al. Among authors: zhang y. Nature. 2019 Aug;572(7767):80-85. doi: 10.1038/s41586-019-1337-6. Epub 2019 Jun 26. Nature. 2019. PMID: 31243364 Free PMC article.
Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.
Liang YL, Belousoff MJ, Zhao P, Koole C, Fletcher MM, Truong TT, Julita V, Christopoulos G, Xu HE, Zhang Y, Khoshouei M, Christopoulos A, Danev R, Sexton PM, Wootten D. Liang YL, et al. Among authors: zhang y. Mol Cell. 2020 Feb 6;77(3):656-668.e5. doi: 10.1016/j.molcel.2020.01.012. Epub 2020 Jan 30. Mol Cell. 2020. PMID: 32004469 Free article.
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir.
Yin W, Mao C, Luan X, Shen DD, Shen Q, Su H, Wang X, Zhou F, Zhao W, Gao M, Chang S, Xie YC, Tian G, Jiang HW, Tao SC, Shen J, Jiang Y, Jiang H, Xu Y, Zhang S, Zhang Y, Xu HE. Yin W, et al. Among authors: zhang s, zhang y. Science. 2020 Jun 26;368(6498):1499-1504. doi: 10.1126/science.abc1560. Epub 2020 May 1. Science. 2020. PMID: 32358203 Free PMC article.
Cryo-EM structures of inactive and active GABAB receptor.
Mao C, Shen C, Li C, Shen DD, Xu C, Zhang S, Zhou R, Shen Q, Chen LN, Jiang Z, Liu J, Zhang Y. Mao C, et al. Among authors: zhang s, zhang y. Cell Res. 2020 Jul;30(7):564-573. doi: 10.1038/s41422-020-0350-5. Epub 2020 Jun 3. Cell Res. 2020. PMID: 32494023 Free PMC article.
Structural basis of GPBAR activation and bile acid recognition.
Yang F, Mao C, Guo L, Lin J, Ming Q, Xiao P, Wu X, Shen Q, Guo S, Shen DD, Lu R, Zhang L, Huang S, Ping Y, Zhang C, Ma C, Zhang K, Liang X, Shen Y, Nan F, Yi F, Luca VC, Zhou J, Jiang C, Sun JP, Xie X, Yu X, Zhang Y. Yang F, et al. Among authors: zhang l, zhang c, zhang k, zhang y. Nature. 2020 Nov;587(7834):499-504. doi: 10.1038/s41586-020-2569-1. Epub 2020 Jul 22. Nature. 2020. PMID: 32698187
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