Zhang Y - Search Results

1

Evaluation of Heterocyclic Carboxamides as Potential Efflux Pump Inhibitors in Pseudomonas aeruginosa.

Yuan Y, Rosado-Lugo JD, Zhang Y, Datta P, Sun Y, Cao Y, Banerjee A, Parhi AK. Yuan Y, et al. Among authors: zhang y. Antibiotics (Basel). 2021 Dec 28;11(1):30. doi: 10.3390/antibiotics11010030. Antibiotics (Basel). 2021. PMID: 35052908 Free PMC article.

2

Evaluation of 2,6-difluoro-3-(oxazol-2-ylmethoxy)benzamide chemotypes as Gram-negative FtsZ inhibitors.

Rosado-Lugo JD, Sun Y, Banerjee A, Cao Y, Datta P, Zhang Y, Yuan Y, Parhi AK. Rosado-Lugo JD, et al. Among authors: zhang y. J Antibiot (Tokyo). 2022 Jul;75(7):385-395. doi: 10.1038/s41429-022-00531-9. Epub 2022 May 26. J Antibiot (Tokyo). 2022. PMID: 35618784

3

Evaluation of a Conformationally Constrained Indole Carboxamide as a Potential Efflux Pump Inhibitor in Pseudomonas aeruginosa.

Zhang Y, Rosado-Lugo JD, Datta P, Sun Y, Cao Y, Banerjee A, Yuan Y, Parhi AK. Zhang Y, et al. Antibiotics (Basel). 2022 May 26;11(6):716. doi: 10.3390/antibiotics11060716. Antibiotics (Basel). 2022. PMID: 35740123 Free PMC article.

4

Inhibition of RND-type efflux pumps confers the FtsZ-directed prodrug TXY436 with activity against Gram-negative bacteria.

Kaul M, Zhang Y, Parhi AK, Lavoie EJ, Pilch DS. Kaul M, et al. Among authors: zhang y. Biochem Pharmacol. 2014 Jun 1;89(3):321-8. doi: 10.1016/j.bcp.2014.03.002. Epub 2014 Mar 14. Biochem Pharmacol. 2014. PMID: 24637241

5

Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents.

Zhang Y, Giurleo D, Parhi A, Kaul M, Pilch DS, LaVoie EJ. Zhang Y, et al. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2001-6. doi: 10.1016/j.bmcl.2013.02.016. Epub 2013 Feb 13. Bioorg Med Chem Lett. 2013. PMID: 23481648 Free PMC article.

6

Pharmacokinetics and in vivo antistaphylococcal efficacy of TXY541, a 1-methylpiperidine-4-carboxamide prodrug of PC190723.

Kaul M, Mark L, Zhang Y, Parhi AK, LaVoie EJ, Pilch DS. Kaul M, et al. Among authors: zhang y. Biochem Pharmacol. 2013 Dec 15;86(12):1699-707. doi: 10.1016/j.bcp.2013.10.010. Epub 2013 Oct 20. Biochem Pharmacol. 2013. PMID: 24148278

7

TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus.

Kaul M, Mark L, Zhang Y, Parhi AK, Lyu YL, Pawlak J, Saravolatz S, Saravolatz LD, Weinstein MP, LaVoie EJ, Pilch DS. Kaul M, et al. Among authors: zhang y. Antimicrob Agents Chemother. 2015 Aug;59(8):4845-55. doi: 10.1128/AAC.00708-15. Epub 2015 Jun 1. Antimicrob Agents Chemother. 2015. PMID: 26033735 Free PMC article.

8

Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines.

Parhi AK, Zhang Y, Saionz KW, Pradhan P, Kaul M, Trivedi K, Pilch DS, LaVoie EJ. Parhi AK, et al. Among authors: zhang y. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4968-74. doi: 10.1016/j.bmcl.2013.06.048. Epub 2013 Jun 26. Bioorg Med Chem Lett. 2013. PMID: 23891185 Free PMC article.

9

3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents.

Kelley C, Zhang Y, Parhi A, Kaul M, Pilch DS, LaVoie EJ. Kelley C, et al. Among authors: zhang y. Bioorg Med Chem. 2012 Dec 15;20(24):7012-29. doi: 10.1016/j.bmc.2012.10.009. Epub 2012 Oct 17. Bioorg Med Chem. 2012. PMID: 23127490 Free PMC article.

10

Enterococcal and streptococcal resistance to PC190723 and related compounds: molecular insights from a FtsZ mutational analysis.

Kaul M, Zhang Y, Parhi AK, Lavoie EJ, Tuske S, Arnold E, Kerrigan JE, Pilch DS. Kaul M, et al. Among authors: zhang y. Biochimie. 2013 Oct;95(10):1880-7. doi: 10.1016/j.biochi.2013.06.010. Epub 2013 Jun 25. Biochimie. 2013. PMID: 23806423 Free PMC article.

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