Zhang Y - Search Results

1

Five-day water-only fasting decreased metabolic-syndrome risk factors and increased anti-aging biomarkers without toxicity in a clinical trial of normal-weight individuals.

Jiang Y, Yang X, Dong C, Lu Y, Yin H, Xiao B, Yang X, Chen W, Cheng W, Tian H, Guo L, Hu X, Fang H, Chen W, Li Z, Zhou W, Sun W, Guo X, Li S, Lin Y, He R, Chen X, Liu D, Zhang M, Zhang Y, Zhao H, Zheng P, Seyfried TN, Hoffman RM, Jia W, Ji G, Jia L. Jiang Y, et al. Among authors: zhang m, zhang y. Clin Transl Med. 2021 Aug;11(8):e502. doi: 10.1002/ctm2.502. Clin Transl Med. 2021. PMID: 34459130 Free PMC article. No abstract available.

2

Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4-CHOP-DR5 Axis in Human Esophageal Cancer Cells.

Chen P, Hu T, Liang Y, Li P, Chen X, Zhang J, Ma Y, Hao Q, Wang J, Zhang P, Zhang Y, Zhao H, Yang S, Yu J, Jeong LS, Qi H, Yang M, Hoffman RM, Dong Z, Jia L. Chen P, et al. Among authors: zhang p, zhang j, zhang y. Clin Cancer Res. 2016 Aug 15;22(16):4145-57. doi: 10.1158/1078-0432.CCR-15-2254. Epub 2016 Mar 16. Clin Cancer Res. 2016. PMID: 26983464

3

Radiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells.

Wang X, Zhang W, Yan Z, Liang Y, Li L, Yu X, Feng Y, Fu S, Zhang Y, Zhao H, Yu J, Jeong LS, Guo X, Jia L. Wang X, et al. Among authors: zhang w, zhang y. Oncotarget. 2016 Jun 21;7(25):38380-38391. doi: 10.18632/oncotarget.9526. Oncotarget. 2016. PMID: 27224919 Free PMC article.

4

Targeting neddylation pathway with MLN4924 (Pevonedistat) induces NOXA-dependent apoptosis in renal cell carcinoma.

Wang J, Wang S, Zhang W, Wang X, Liu X, Liu L, Li L, Liang Y, Yu J, Jeong LS, Jia L, Zhao H, Zhang Y. Wang J, et al. Among authors: zhang w, zhang y. Biochem Biophys Res Commun. 2017 Sep 2;490(4):1183-1188. doi: 10.1016/j.bbrc.2017.06.179. Epub 2017 Jun 29. Biochem Biophys Res Commun. 2017. PMID: 28669728

5

The Nedd8-activating enzyme inhibitor MLN4924 (TAK-924/Pevonedistat) induces apoptosis via c-Myc-Noxa axis in head and neck squamous cell carcinoma.

Zhang W, Liang Y, Li L, Wang X, Yan Z, Dong C, Zeng MS, Zhong Q, Liu XK, Yu J, Sun S, Liu X, Kang J, Zhao H, Jeong LS, Zhang Y, Jia L. Zhang W, et al. Among authors: zhang y. Cell Prolif. 2019 Mar;52(2):e12536. doi: 10.1111/cpr.12536. Epub 2018 Oct 19. Cell Prolif. 2019. PMID: 30341788 Free PMC article.

6

Neddylation Inactivation Facilitates FOXO3a Nuclear Export to Suppress Estrogen Receptor Transcription and Improve Fulvestrant Sensitivity.

Jia X, Li C, Li L, Liu X, Zhou L, Zhang W, Ni S, Lu Y, Chen L, Jeong LS, Yu J, Zhang Y, Zhang J, He S, Hu X, Sun H, Yu K, Liu G, Zhao H, Zhang Y, Jia L, Shao ZM. Jia X, et al. Among authors: zhang w, zhang j, zhang y. Clin Cancer Res. 2019 Jun 15;25(12):3658-3672. doi: 10.1158/1078-0432.CCR-18-2434. Epub 2019 Mar 4. Clin Cancer Res. 2019. PMID: 30833270

7

Promotion of tumor-associated macrophages infiltration by elevated neddylation pathway via NF-κB-CCL2 signaling in lung cancer.

Zhou L, Jiang Y, Liu X, Li L, Yang X, Dong C, Liu X, Lin Y, Li Y, Yu J, He R, Huang S, Liu G, Zhang Y, Jeong LS, Hoffman RM, Jia L. Zhou L, et al. Among authors: zhang y. Oncogene. 2019 Jul;38(29):5792-5804. doi: 10.1038/s41388-019-0840-4. Epub 2019 Jun 26. Oncogene. 2019. PMID: 31243299

8

Effective targeting of the ubiquitin-like modifier NEDD8 for lung adenocarcinoma treatment.

Jiang Y, Cheng W, Li L, Zhou L, Liang Y, Zhang W, Chen W, Wang S, Zhao H, Chen G, Zhou W, Ji G, Zhang Y, Hoffman RM, Wang M, Jia L. Jiang Y, et al. Among authors: zhang w, zhang y. Cell Biol Toxicol. 2020 Aug;36(4):349-364. doi: 10.1007/s10565-019-09503-6. Epub 2020 Jan 6. Cell Biol Toxicol. 2020. PMID: 31907687

9

The CRL3^BTBD9 E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migration.

Li L, Zhang W, Liu Y, Liu X, Cai L, Kang J, Zhang Y, Chen W, Dong C, Zhang Y, Wang M, Wei W, Jia L. Li L, et al. Among authors: zhang w, zhang y. Signal Transduct Target Ther. 2020 Apr 24;5(1):42. doi: 10.1038/s41392-020-0140-z. Signal Transduct Target Ther. 2020. PMID: 32327643 Free PMC article.

10

NEDD8-conjugating enzyme UBC12 as a novel therapeutic target in esophageal squamous cell carcinoma.

Wang S, Xian J, Li L, Jiang Y, Liu Y, Cai L, Hoffman RM, Jia L, Zhao H, Zhang Y. Wang S, et al. Among authors: zhang y. Signal Transduct Target Ther. 2020 Jul 10;5(1):123. doi: 10.1038/s41392-020-00226-3. Signal Transduct Target Ther. 2020. PMID: 32651357 Free PMC article. No abstract available.

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