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Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita.
Nachmani D, Bothmer AH, Grisendi S, Mele A, Bothmer D, Lee JD, Monteleone E, Cheng K, Zhang Y, Bester AC, Guzzetti A, Mitchell CA, Mendez LM, Pozdnyakova O, Sportoletti P, Martelli MP, Vulliamy TJ, Safra M, Schwartz S, Luzzatto L, Bluteau O, Soulier J, Darnell RB, Falini B, Dokal I, Ito K, Clohessy JG, Pandolfi PP. Nachmani D, et al. Among authors: zhang y. Nat Genet. 2019 Oct;51(10):1518-1529. doi: 10.1038/s41588-019-0502-z. Epub 2019 Sep 30. Nat Genet. 2019. PMID: 31570891 Free PMC article.
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.
Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP. Lee YR, et al. Among authors: zhang j, zhang y. Science. 2019 May 17;364(6441):eaau0159. doi: 10.1126/science.aau0159. Science. 2019. PMID: 31097636 Free PMC article.
Intragenic antagonistic roles of protein and circRNA in tumorigenesis.
Guarnerio J, Zhang Y, Cheloni G, Panella R, Mae Katon J, Simpson M, Matsumoto A, Papa A, Loretelli C, Petri A, Kauppinen S, Garbutt C, Nielsen GP, Deshpande V, Castillo-Martin M, Cordon-Cardo C, Dimitrios S, Clohessy JG, Batish M, Pandolfi PP. Guarnerio J, et al. Among authors: zhang y. Cell Res. 2019 Aug;29(8):628-640. doi: 10.1038/s41422-019-0192-1. Epub 2019 Jun 17. Cell Res. 2019. PMID: 31209250 Free PMC article.
Author Correction: Intragenic antagonistic roles of protein and circRNA in tumorigenesis.
Guarnerio J, Zhang Y, Cheloni G, Panella R, Katon JM, Simpson M, Matsumoto A, Papa A, Loretelli C, Petri A, Kauppinen S, Garbutt C, Nielsen GP, Deshpande V, Castillo-Martin M, Cordon-Cardo C, Spentzos D, Clohessy JG, Batish M, Pandolfi PP. Guarnerio J, et al. Among authors: zhang y. Cell Res. 2020 Feb;30(2):188. doi: 10.1038/s41422-019-0262-4. Cell Res. 2020. PMID: 31911670 Free PMC article.
PTENP1 is a ceRNA for PTEN: it's CRISPR clear.
Vitiello M, Evangelista M, Zhang Y, Salmena L, Pandolfi PP, Poliseno L. Vitiello M, et al. Among authors: zhang y. J Hematol Oncol. 2020 Jun 9;13(1):73. doi: 10.1186/s13045-020-00894-2. J Hematol Oncol. 2020. PMID: 32517731 Free PMC article.
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