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The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Xia Y, Xie Y, Yu Z, Xiao H, Jiang G, Zhou X, Yang Y, Li X, Zhao M, Li L, Zheng M, Han S, Zong Z, Meng X, Deng H, Ye H, Fa Y, Wu H, Oldfield E, Hu X, Liu W, Shi Y, Zhang Y. Xia Y, et al. Among authors: zhang y. Cell. 2018 Nov 1;175(4):1059-1073.e21. doi: 10.1016/j.cell.2018.08.070. Epub 2018 Sep 27. Cell. 2018. PMID: 30270039 Free article.
Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates.
Hudock MP, Sanz-Rodríguez CE, Song Y, Chan JM, Zhang Y, Odeh S, Kosztowski T, Leon-Rossell A, Concepción JL, Yardley V, Croft SL, Urbina JA, Oldfield E. Hudock MP, et al. Among authors: zhang y. J Med Chem. 2006 Jan 12;49(1):215-23. doi: 10.1021/jm0582625. J Med Chem. 2006. PMID: 16392806
Structural studies of Vgamma2Vdelta2 T cell phosphoantigens.
Zhang Y, Song Y, Yin F, Broderick E, Siegel K, Goddard A, Nieves E, Pasa-Tolic L, Tanaka Y, Wang H, Morita CT, Oldfield E. Zhang Y, et al. Chem Biol. 2006 Sep;13(9):985-92. doi: 10.1016/j.chembiol.2006.08.007. Chem Biol. 2006. PMID: 16984888
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.
Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH. Guo RT, et al. Among authors: zhang y. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10022-7. doi: 10.1073/pnas.0702254104. Epub 2007 May 29. Proc Natl Acad Sci U S A. 2007. PMID: 17535895 Free PMC article.
Activity of sulfonium bisphosphonates on tumor cell lines.
Zhang Y, Hudock MP, Krysiak K, Cao R, Bergan K, Yin F, Leon A, Oldfield E. Zhang Y, et al. J Med Chem. 2007 Nov 29;50(24):6067-79. doi: 10.1021/jm700991k. Epub 2007 Oct 27. J Med Chem. 2007. PMID: 17963374
Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
Zhang Y, Cao R, Yin F, Hudock MP, Guo RT, Krysiak K, Mukherjee S, Gao YG, Robinson H, Song Y, No JH, Bergan K, Leon A, Cass L, Goddard A, Chang TK, Lin FY, Van Beek E, Papapoulos S, Wang AH, Kubo T, Ochi M, Mukkamala D, Oldfield E. Zhang Y, et al. J Am Chem Soc. 2009 Apr 15;131(14):5153-62. doi: 10.1021/ja808285e. J Am Chem Soc. 2009. PMID: 19309137 Free PMC article.
238,417 results
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