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Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci.
Earley EJ, Kelly S, Fang F, Alencar CS, Rodrigues DOW, Soares Cruz DT, Flanagan JM, Ware RE, Zhang X, Gordeuk V, Gladwin M, Zhang Y, Nouraie M, Nekhai S, Sabino E, Custer B, Dinardo C, Page GP; International Component of the NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III) and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Earley EJ, et al. Among authors: zhang x, zhang y. Br J Haematol. 2023 Apr;201(2):343-352. doi: 10.1111/bjh.18637. Epub 2023 Jan 5. Br J Haematol. 2023. PMID: 36602125 Free PMC article.
Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease.
Zhang X, Zhang W, Ma SF, Desai AA, Saraf S, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Abbasi T, Casanova NG, Steinberg MH, Baldwin CT, Sebastiani P, Prchal JT, Kittles R, Garcia JG, Machado RF, Gordeuk VR. Zhang X, et al. Among authors: zhang w. Circulation. 2014 Apr 22;129(16):1650-8. doi: 10.1161/CIRCULATIONAHA.113.005296. Epub 2014 Feb 10. Circulation. 2014. PMID: 24515990 Free PMC article.
Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease.
Zhang X, Zhang W, Saraf SL, Nouraie M, Han J, Gowhari M, Hassan J, Miasnikova G, Sergueeva A, Nekhai S, Kittles R, Machado RF, Garcia JG, Gladwin MT, Steinberg MH, Sebastiani P, McClain DA, Gordeuk VR. Zhang X, et al. Among authors: zhang w. Hum Genet. 2015 Aug;134(8):895-904. doi: 10.1007/s00439-015-1572-3. Epub 2015 May 30. Hum Genet. 2015. PMID: 26025476 Free PMC article.
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Saraf SL, Zhang X, Shah B, Kanias T, Gudehithlu KP, Kittles R, Machado RF, Arruda JA, Gladwin MT, Singh AK, Gordeuk VR. Saraf SL, et al. Among authors: zhang x. Haematologica. 2015 Oct;100(10):1275-84. doi: 10.3324/haematol.2015.124875. Epub 2015 Jul 23. Haematologica. 2015. PMID: 26206798 Free PMC article.
Patterns of opioid use in sickle cell disease.
Han J, Saraf SL, Zhang X, Gowhari M, Molokie RE, Hassan J, Alhandalous C, Jain S, Younge J, Abbasi T, Machado RF, Gordeuk VR. Han J, et al. Among authors: zhang x. Am J Hematol. 2016 Nov;91(11):1102-1106. doi: 10.1002/ajh.24498. Epub 2016 Aug 8. Am J Hematol. 2016. PMID: 27466799 Free PMC article.
APOL1, α-thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia.
Saraf SL, Shah BN, Zhang X, Han J, Tayo BO, Abbasi T, Ostrower A, Guzman E, Molokie RE, Gowhari M, Hassan J, Jain S, Cooper RS, Machado RF, Lash JP, Gordeuk VR. Saraf SL, et al. Among authors: zhang x. Haematologica. 2017 Jan;102(1):e1-e6. doi: 10.3324/haematol.2016.154153. Epub 2016 Sep 22. Haematologica. 2017. PMID: 27658436 Free PMC article. No abstract available.
Prospective study of thrombosis and thrombospondin-1 expression in Chuvash polycythemia.
Sergueeva A, Miasnikova G, Shah BN, Song J, Lisina E, Okhotin DJ, Nouraie M, Nekhai S, Ammosova T, Niu XM, Prchal JT, Zhang X, Gordeuk VR. Sergueeva A, et al. Among authors: zhang x. Haematologica. 2017 May;102(5):e166-e169. doi: 10.3324/haematol.2016.158170. Epub 2017 Jan 19. Haematologica. 2017. PMID: 28104701 Free PMC article. No abstract available.
Association of circulating transcriptomic profiles with mortality in sickle cell disease.
Desai AA, Lei Z, Bahroos N, Maienschein-Cline M, Saraf SL, Zhang X, Shah BN, Nouraie SM, Abbasi T, Patel AR, Lang RM, Lussier Y, Garcia JGN, Gordeuk VR, Machado RF. Desai AA, et al. Among authors: zhang x. Blood. 2017 Jun 1;129(22):3009-3016. doi: 10.1182/blood-2016-11-752279. Epub 2017 Apr 3. Blood. 2017. PMID: 28373264 Free PMC article.
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