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Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming.
Morrissey SM, Zhang F, Ding C, Montoya-Durango DE, Hu X, Yang C, Wang Z, Yuan F, Fox M, Zhang HG, Guo H, Tieri D, Kong M, Watson CT, Mitchell RA, Zhang X, McMasters KM, Huang J, Yan J. Morrissey SM, et al. Among authors: zhang f, zhang hg, zhang x. Cell Metab. 2021 Oct 5;33(10):2040-2058.e10. doi: 10.1016/j.cmet.2021.09.002. Epub 2021 Sep 23. Cell Metab. 2021. PMID: 34559989 Free PMC article.
Plant-Derived Exosomal Nanoparticles Inhibit Pathogenicity of Porphyromonas gingivalis.
Sundaram K, Miller DP, Kumar A, Teng Y, Sayed M, Mu J, Lei C, Sriwastva MK, Zhang L, Yan J, Merchant ML, He L, Fang Y, Zhang S, Zhang X, Park JW, Lamont RJ, Zhang HG. Sundaram K, et al. Among authors: zhang l, zhang s, zhang hg, zhang x. iScience. 2019 Nov 22;21:308-327. doi: 10.1016/j.isci.2019.10.032. Epub 2019 Oct 21. iScience. 2019. PMID: 31678913 Free PMC article.
Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer.
Liu M, Tong Z, Ding C, Luo F, Wu S, Wu C, Albeituni S, He L, Hu X, Tieri D, Rouchka EC, Hamada M, Takahashi S, Gibb AA, Kloecker G, Zhang HG, Bousamra M 2nd, Hill BG, Zhang X, Yan J. Liu M, et al. Among authors: zhang hg, zhang x. J Clin Invest. 2020 Apr 1;130(4):2081-2096. doi: 10.1172/JCI131335. J Clin Invest. 2020. PMID: 31945018 Free PMC article.
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance.
Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG. Kumar A, et al. Among authors: zhang l, zhang s, zhang hg, zhang x. Nat Commun. 2021 Jan 11;12(1):213. doi: 10.1038/s41467-020-20500-w. Nat Commun. 2021. PMID: 33431899 Free PMC article.
miR-375 prevents high-fat diet-induced insulin resistance and obesity by targeting the aryl hydrocarbon receptor and bacterial tryptophanase (tnaA) gene.
Kumar A, Ren Y, Sundaram K, Mu J, Sriwastva MK, Dryden GW, Lei C, Zhang L, Yan J, Zhang X, Park JW, Merchant ML, Teng Y, Zhang HG. Kumar A, et al. Among authors: zhang l, zhang hg, zhang x. Theranostics. 2021 Feb 19;11(9):4061-4077. doi: 10.7150/thno.52558. eCollection 2021. Theranostics. 2021. PMID: 33754048 Free PMC article.
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
Teng Y, Xu F, Zhang X, Mu J, Sayed M, Hu X, Lei C, Sriwastva M, Kumar A, Sundaram K, Zhang L, Park JW, Chen SY, Zhang S, Yan J, Merchant ML, Zhang X, McClain CJ, Wolfe JK, Adcock RS, Chung D, Palmer KE, Zhang HG. Teng Y, et al. Among authors: zhang l, zhang s, zhang hg, zhang x. Mol Ther. 2021 Aug 4;29(8):2424-2440. doi: 10.1016/j.ymthe.2021.05.005. Epub 2021 May 11. Mol Ther. 2021. PMID: 33984520 Free PMC article.
Lemon exosome-like nanoparticles enhance stress survival of gut bacteria by RNase P-mediated specific tRNA decay.
Lei C, Teng Y, He L, Sayed M, Mu J, Xu F, Zhang X, Kumar A, Sundaram K, Sriwastva MK, Zhang L, Chen SY, Feng W, Zhang S, Yan J, Park JW, Merchant ML, Zhang X, Zhang HG. Lei C, et al. Among authors: zhang l, zhang s, zhang hg, zhang x. iScience. 2021 May 5;24(6):102511. doi: 10.1016/j.isci.2021.102511. eCollection 2021 Jun 25. iScience. 2021. PMID: 34142028 Free PMC article.
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