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Structure-Guided Design of G-Protein-Coupled Receptor Polypharmacology.
Kampen S, Duy Vo D, Zhang X, Panel N, Yang Y, Jaiteh M, Matricon P, Svenningsson P, Brea J, Loza MI, Kihlberg J, Carlsson J. Kampen S, et al. Among authors: zhang x. Angew Chem Int Ed Engl. 2021 Aug 9;60(33):18022-18030. doi: 10.1002/anie.202101478. Epub 2021 Jul 16. Angew Chem Int Ed Engl. 2021. PMID: 33904641 Free PMC article.
Antidepressants reverse the attenuation of the neurotrophic MEK/MAPK cascade in frontal cortex by elevated platform stress; reversal of effects on LTP is associated with GluA1 phosphorylation.
Qi H, Mailliet F, Spedding M, Rocher C, Zhang X, Delagrange P, McEwen B, Jay TM, Svenningsson P. Qi H, et al. Among authors: zhang x. Neuropharmacology. 2009 Jan;56(1):37-46. doi: 10.1016/j.neuropharm.2008.06.068. Epub 2008 Jul 9. Neuropharmacology. 2009. PMID: 18657555
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