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On the genetic basis of tail-loss evolution in humans and apes.
Xia B, Zhang W, Zhao G, Zhang X, Bai J, Brosh R, Wudzinska A, Huang E, Ashe H, Ellis G, Pour M, Zhao Y, Coelho C, Zhu Y, Miller A, Dasen JS, Maurano MT, Kim SY, Boeke JD, Yanai I. Xia B, et al. Among authors: zhang w, zhang x. Nature. 2024 Feb;626(8001):1042-1048. doi: 10.1038/s41586-024-07095-8. Epub 2024 Feb 28. Nature. 2024. PMID: 38418917 Free PMC article.
Mouse genome rewriting and tailoring of three important disease loci.
Zhang W, Golynker I, Brosh R, Fajardo A, Zhu Y, Wudzinska AM, Ordoñez R, Ribeiro-Dos-Santos AM, Carrau L, Damani-Yokota P, Yeung ST, Khairallah C, Vela Gartner A, Chalhoub N, Huang E, Ashe HJ, Khanna KM, Maurano MT, Kim SY, tenOever BR, Boeke JD. Zhang W, et al. Nature. 2023 Nov;623(7986):423-431. doi: 10.1038/s41586-023-06675-4. Epub 2023 Nov 1. Nature. 2023. PMID: 37914927 Free PMC article.
Large-scale genomic rearrangements boost SCRaMbLE in Saccharomyces cerevisiae.
Cheng L, Zhao S, Li T, Hou S, Luo Z, Xu J, Yu W, Jiang S, Monti M, Schindler D, Zhang W, Hou C, Ma Y, Cai Y, Boeke JD, Dai J. Cheng L, et al. Among authors: zhang w. Nat Commun. 2024 Jan 26;15(1):770. doi: 10.1038/s41467-023-44511-5. Nat Commun. 2024. PMID: 38278805 Free PMC article.
Synthetic Genomes.
Zhang W, Mitchell LA, Bader JS, Boeke JD. Zhang W, et al. Annu Rev Biochem. 2020 Jun 20;89:77-101. doi: 10.1146/annurev-biochem-013118-110704. Annu Rev Biochem. 2020. PMID: 32569517 Review.
Building a eukaryotic chromosome arm by de novo design and synthesis.
Jiang S, Luo Z, Wu J, Yu K, Zhao S, Cai Z, Yu W, Wang H, Cheng L, Liang Z, Gao H, Monti M, Schindler D, Huang L, Zeng C, Zhang W, Zhou C, Tang Y, Li T, Ma Y, Cai Y, Boeke JD, Zhao Q, Dai J. Jiang S, et al. Among authors: zhang w. Nat Commun. 2023 Nov 30;14(1):7886. doi: 10.1038/s41467-023-43531-5. Nat Commun. 2023. PMID: 38036514 Free PMC article.
3D organization of synthetic and scrambled chromosomes.
Mercy G, Mozziconacci J, Scolari VF, Yang K, Zhao G, Thierry A, Luo Y, Mitchell LA, Shen M, Shen Y, Walker R, Zhang W, Wu Y, Xie ZX, Luo Z, Cai Y, Dai J, Yang H, Yuan YJ, Boeke JD, Bader JS, Muller H, Koszul R. Mercy G, et al. Among authors: zhang w. Science. 2017 Mar 10;355(6329):eaaf4597. doi: 10.1126/science.aaf4597. Science. 2017. PMID: 28280150 Free PMC article.
Engineering the ribosomal DNA in a megabase synthetic chromosome.
Zhang W, Zhao G, Luo Z, Lin Y, Wang L, Guo Y, Wang A, Jiang S, Jiang Q, Gong J, Wang Y, Hou S, Huang J, Li T, Qin Y, Dong J, Qin Q, Zhang J, Zou X, He X, Zhao L, Xiao Y, Xu M, Cheng E, Huang N, Zhou T, Shen Y, Walker R, Luo Y, Kuang Z, Mitchell LA, Yang K, Richardson SM, Wu Y, Li BZ, Yuan YJ, Yang H, Lin J, Chen GQ, Wu Q, Bader JS, Cai Y, Boeke JD, Dai J. Zhang W, et al. Among authors: zhang j. Science. 2017 Mar 10;355(6329):eaaf3981. doi: 10.1126/science.aaf3981. Science. 2017. PMID: 28280149
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES.
Luo Z, Wang L, Wang Y, Zhang W, Guo Y, Shen Y, Jiang L, Wu Q, Zhang C, Cai Y, Dai J. Luo Z, et al. Among authors: zhang c, zhang w. Nat Commun. 2018 May 22;9(1):1930. doi: 10.1038/s41467-017-00806-y. Nat Commun. 2018. PMID: 29789541 Free PMC article.
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