Zhang W - Search Results

1

Effect of Itraconazole, a Potent CYP3A4 Inhibitor, on the Steady-State Pharmacokinetics of Vemurafenib in Patients With BRAF^V600 Mutation-Positive Malignancies.

Zhang W, Mathisen M, Goodman GR, Forbes H, Song Y, Bertran E, Demidov L, Shin SJ. Zhang W, et al. Clin Pharmacol Drug Dev. 2021 Jan;10(1):39-45. doi: 10.1002/cpdd.822. Epub 2020 Jun 29. Clin Pharmacol Drug Dev. 2021. PMID: 32602215 Clinical Trial.

2

Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Digoxin in Patients With BRAF^V600 Mutation-Positive Metastatic Malignancy.

Zhang W, McIntyre C, Kuhn M, Forbes H, Kim TM, Lee J, Demidov L, Colburn D. Zhang W, et al. J Clin Pharmacol. 2018 Aug;58(8):1067-1073. doi: 10.1002/jcph.1111. Epub 2018 Apr 12. J Clin Pharmacol. 2018. PMID: 29645280

3

Effect of Rifampicin on the Pharmacokinetics of a Single Dose of Vemurafenib in Patients With BRAF^V600 Mutation-Positive Metastatic Malignancy.

Zhang W, McIntyre C, Forbes H, Gaafar R, Kohail H, Beck JT, Plestina S, Bertran E, Riehl T. Zhang W, et al. Clin Pharmacol Drug Dev. 2019 Aug;8(6):837-843. doi: 10.1002/cpdd.643. Epub 2018 Dec 20. Clin Pharmacol Drug Dev. 2019. PMID: 30570831 Clinical Trial.

4

Absolute Bioavailability of Vemurafenib in Patients With BRAF^V600 Mutation-Positive Malignancies.

Zhang W, Colburn D, Simmons B, Papai Z, Bertran E, Schadt S, Husser C, Forbes H, Roethlisberger D, Hartung T. Zhang W, et al. Clin Pharmacol Drug Dev. 2020 May;9(4):496-504. doi: 10.1002/cpdd.773. Epub 2020 Feb 21. Clin Pharmacol Drug Dev. 2020. PMID: 32083398 Clinical Trial.

5

Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Tizanidine (a CYP1A2 Substrate) in Patients With BRAF^V600 Mutation-Positive Malignancies.

Zhang W, McIntyre C, Riehl T, Forbes H, Bertran E, Choi HJ, Lee DH, Lee J. Zhang W, et al. Clin Pharmacol Drug Dev. 2020 Jul;9(5):651-658. doi: 10.1002/cpdd.788. Epub 2020 Apr 20. Clin Pharmacol Drug Dev. 2020. PMID: 32311241 Clinical Trial.

6

Clinical Pharmacokinetics of Vemurafenib.

Zhang W, Heinzmann D, Grippo JF. Zhang W, et al. Clin Pharmacokinet. 2017 Sep;56(9):1033-1043. doi: 10.1007/s40262-017-0523-7. Clin Pharmacokinet. 2017. PMID: 28255850 Review.

7

The effects of a high-fat meal on single-dose vemurafenib pharmacokinetics.

Ribas A, Zhang W, Chang I, Shirai K, Ernstoff MS, Daud A, Cowey CL, Daniels G, Seja E, O'Laco E, Glaspy JA, Chmielowski B, Hill T, Joe AK, Grippo JF. Ribas A, et al. Among authors: zhang w. J Clin Pharmacol. 2014 Apr;54(4):368-74. doi: 10.1002/jcph.255. Epub 2014 Jan 22. J Clin Pharmacol. 2014. PMID: 24374975 Clinical Trial.

8

Evaluation of the Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose of Emicizumab in Healthy Chinese Subjects.

Li H, Zhang W, Petry C, Li L, Fernandez E, Kiialainen A, Feng S, Hsu W, Li L, Wei Y, Schmitt C. Li H, et al. Among authors: zhang w. Clin Pharmacol Drug Dev. 2021 Jan;10(1):30-38. doi: 10.1002/cpdd.805. Epub 2020 May 20. Clin Pharmacol Drug Dev. 2021. PMID: 32433829 Free PMC article. Clinical Trial.

9

Vemurafenib in Chinese patients with BRAF^V600 mutation-positive unresectable or metastatic melanoma: an open-label, multicenter phase I study.

Si L, Zhang X, Xu Z, Jiang Q, Bu L, Wang X, Mao L, Zhang W, Richie N, Guo J. Si L, et al. Among authors: zhang w, zhang x. BMC Cancer. 2018 May 3;18(1):520. doi: 10.1186/s12885-018-4336-3. BMC Cancer. 2018. PMID: 29724167 Free PMC article. Clinical Trial.

10

BRIM-P: A phase I, open-label, multicenter, dose-escalation study of vemurafenib in pediatric patients with surgically incurable, BRAF mutation-positive melanoma.

Chisholm JC, Suvada J, Dunkel IJ, Casanova M, Zhang W, Ritchie N, Choi Y, Park J, Das Thakur M, Simko S, Wan Rachel Tam N, Ferrari A. Chisholm JC, et al. Among authors: zhang w. Pediatr Blood Cancer. 2018 May;65(5):e26947. doi: 10.1002/pbc.26947. Epub 2018 Jan 19. Pediatr Blood Cancer. 2018. PMID: 29350463 Free PMC article. Clinical Trial.

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