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A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2.
Chen J, Wang P, Yuan L, Zhang L, Zhang L, Zhao H, Chen C, Wang X, Han J, Chen Y, Jia J, Lu Z, Hong J, Lu Z, Wang Q, Chen R, Qi R, Ma J, Zhou M, Yu H, Zhuang C, Liu X, Han Q, Wang G, Su Y, Yuan Q, Cheng T, Wu T, Ye X, Zhang T, Li C, Zhang J, Zhu H, Chen Y, Chen H, Xia N. Chen J, et al. Among authors: zhang l, zhang t, zhang j. Sci Bull (Beijing). 2022 Jul 15;67(13):1372-1387. doi: 10.1016/j.scib.2022.05.018. Epub 2022 May 26. Sci Bull (Beijing). 2022. PMID: 35637645 Free PMC article.
HBV life cycle is restricted in mouse hepatocytes expressing human NTCP.
Li H, Zhuang Q, Wang Y, Zhang T, Zhao J, Zhang Y, Zhang J, Lin Y, Yuan Q, Xia N, Han J. Li H, et al. Among authors: zhang t, zhang j, zhang y. Cell Mol Immunol. 2014 Mar;11(2):175-83. doi: 10.1038/cmi.2013.66. Epub 2014 Feb 10. Cell Mol Immunol. 2014. PMID: 24509445 Free PMC article.
Prolonged suppression of HBV in mice by a novel antibody that targets a unique epitope on hepatitis B surface antigen.
Zhang TY, Yuan Q, Zhao JH, Zhang YL, Yuan LZ, Lan Y, Lo YC, Sun CP, Wu CR, Zhang JF, Zhang Y, Cao JL, Guo XR, Liu X, Mo XB, Luo WX, Cheng T, Chen YX, Tao MH, Shih JW, Zhao QJ, Zhang J, Chen PJ, Yuan YA, Xia NS. Zhang TY, et al. Among authors: zhang jf, zhang j, zhang yl, zhang y. Gut. 2016 Apr;65(4):658-71. doi: 10.1136/gutjnl-2014-308964. Epub 2015 Sep 30. Gut. 2016. PMID: 26423112
Serum hepatitis B virus RNA is encapsidated pregenome RNA that may be associated with persistence of viral infection and rebound.
Wang J, Shen T, Huang X, Kumar GR, Chen X, Zeng Z, Zhang R, Chen R, Li T, Zhang T, Yuan Q, Li PC, Huang Q, Colonno R, Jia J, Hou J, McCrae MA, Gao Z, Ren H, Xia N, Zhuang H, Lu F. Wang J, et al. Among authors: zhang r, zhang t. J Hepatol. 2016 Oct;65(4):700-710. doi: 10.1016/j.jhep.2016.05.029. Epub 2016 May 28. J Hepatol. 2016. PMID: 27245431 Free article.
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