Zhang SP - Search Results

1

Discovery of piperidine carboxamide TRPV1 antagonists.

Cheung WS, Calvo RR, Tounge BA, Zhang SP, Stone DR, Brandt MR, Hutchinson T, Flores CM, Player MR. Cheung WS, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4569-72. doi: 10.1016/j.bmcl.2008.07.035. Epub 2008 Jul 15. Bioorg Med Chem Lett. 2008. PMID: 18662879

2

Heteroaryl beta-tetralin ureas as novel antagonists of human TRPV1.

Jetter MC, Youngman MA, McNally JJ, McDonnell ME, Zhang SP, Dubin AE, Nasser N, Codd EE, Flores CM, Dax SL. Jetter MC, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6160-3. doi: 10.1016/j.bmcl.2007.09.036. Epub 2007 Sep 12. Bioorg Med Chem Lett. 2007. PMID: 17892935

3

N-pyridin-3-yl- and N-quinolin-3-yl-benzamides: modulators of human vanilloid receptor 1 (TRPV1).

Jetter MC, McNally JJ, Youngman MA, McDonnell ME, Dubin AE, Nasser N, Zhang SP, Codd EE, Colburn RW, Stone DR, Brandt MR, Flores CM, Dax SL. Jetter MC, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2730-4. doi: 10.1016/j.bmcl.2008.02.075. Epub 2008 Mar 5. Bioorg Med Chem Lett. 2008. PMID: 18359227

4

Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep).

Parsons WH, Calvo RR, Cheung W, Lee YK, Patel S, Liu J, Youngman MA, Dax SL, Stone D, Qin N, Hutchinson T, Lubin ML, Zhang SP, Finley M, Liu Y, Brandt MR, Flores CM, Player MR. Parsons WH, et al. Among authors: zhang sp. J Med Chem. 2015 May 14;58(9):3859-74. doi: 10.1021/acs.jmedchem.5b00132. Epub 2015 Apr 15. J Med Chem. 2015. PMID: 25850459

5

The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL).

Zhu B, Connolly PJ, Zhang SP, Chevalier KM, Milligan CM, Flores CM, Macielag MJ. Zhu B, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2020 Jun 15;30(12):127198. doi: 10.1016/j.bmcl.2020.127198. Epub 2020 Apr 18. Bioorg Med Chem Lett. 2020. PMID: 32334914

6

The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors.

Zhu B, Connolly PJ, Zhang YM, McDonnell ME, Bian H, Lin SC, Liu L, Zhang SP, Chevalier KM, Brandt MR, Milligan CM, Flores CM, Macielag MJ. Zhu B, et al. Among authors: zhang ym, zhang sp. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127243. doi: 10.1016/j.bmcl.2020.127243. Epub 2020 May 7. Bioorg Med Chem Lett. 2020. PMID: 32527545

7

7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1.

McDonnell ME, Zhang SP, Nasser N, Dubin AE, Dax SL. McDonnell ME, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2004 Jan 19;14(2):531-4. doi: 10.1016/j.bmcl.2003.09.090. Bioorg Med Chem Lett. 2004. PMID: 14698197

8

N-isoquinolin-5-yl-N'-aralkyl-urea and -amide antagonists of human vanilloid receptor 1.

Jetter MC, Youngman MA, McNally JJ, Zhang SP, Dubin AE, Nasser N, Dax SL. Jetter MC, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3053-6. doi: 10.1016/j.bmcl.2004.04.038. Bioorg Med Chem Lett. 2004. PMID: 15149643

9

Design and synthesis of novel pyrrolidine-containing bradykinin antagonists.

Lee J, Reynolds C, Jetter MC, Youngman MA, Hlasta DJ, Dax SL, Stone DJ, Zhang SP, Codd EE. Lee J, et al. Among authors: zhang sp. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1879-82. doi: 10.1016/s0960-894x(03)00309-3. Bioorg Med Chem Lett. 2003. PMID: 12749889

10

Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range.

Codd EE, Ma J, Zhang SP, Stone DJ Jr, Colburn RW, Brandt MR, Chevalier KM, Zhu Y, Peng S, Cai C, Acton PD, Flores CM. Codd EE, et al. Among authors: zhang sp. Pharmacol Biochem Behav. 2010 Aug;96(2):130-5. doi: 10.1016/j.pbb.2010.04.020. Epub 2010 May 12. Pharmacol Biochem Behav. 2010. PMID: 20438745

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