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Rho-kinase: regulation, (dys)function, and inhibition.
Amin E, Dubey BN, Zhang SC, Gremer L, Dvorsky R, Moll JM, Taha MS, Nagel-Steger L, Piekorz RP, Somlyo AV, Ahmadian MR. Amin E, et al. Among authors: zhang sc. Biol Chem. 2013 Nov;394(11):1399-410. doi: 10.1515/hsz-2013-0181. Biol Chem. 2013. PMID: 23950574 Free PMC article. Review.
Functional cross-talk between ras and rho pathways: a Ras-specific GTPase-activating protein (p120RasGAP) competitively inhibits the RhoGAP activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine finger.
Jaiswal M, Dvorsky R, Amin E, Risse SL, Fansa EK, Zhang SC, Taha MS, Gauhar AR, Nakhaei-Rad S, Kordes C, Koessmeier KT, Cirstea IC, Olayioye MA, Häussinger D, Ahmadian MR. Jaiswal M, et al. Among authors: zhang sc. J Biol Chem. 2014 Mar 7;289(10):6839-6849. doi: 10.1074/jbc.M113.527655. Epub 2014 Jan 17. J Biol Chem. 2014. PMID: 24443565 Free PMC article.
Interaction characteristics of Plexin-B1 with Rho family proteins.
Fansa EK, Dvorsky R, Zhang SC, Fiegen D, Ahmadian MR. Fansa EK, et al. Among authors: zhang sc. Biochem Biophys Res Commun. 2013 May 17;434(4):785-90. doi: 10.1016/j.bbrc.2013.04.012. Epub 2013 Apr 17. Biochem Biophys Res Commun. 2013. PMID: 23603360
Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis.
Flex E, Jaiswal M, Pantaleoni F, Martinelli S, Strullu M, Fansa EK, Caye A, De Luca A, Lepri F, Dvorsky R, Pannone L, Paolacci S, Zhang SC, Fodale V, Bocchinfuso G, Rossi C, Burkitt-Wright EM, Farrotti A, Stellacci E, Cecchetti S, Ferese R, Bottero L, Castro S, Fenneteau O, Brethon B, Sanchez M, Roberts AE, Yntema HG, Van Der Burgt I, Cianci P, Bondeson ML, Cristina Digilio M, Zampino G, Kerr B, Aoki Y, Loh ML, Palleschi A, Di Schiavi E, Carè A, Selicorni A, Dallapiccola B, Cirstea IC, Stella L, Zenker M, Gelb BD, Cavé H, Ahmadian MR, Tartaglia M. Flex E, et al. Among authors: zhang sc. Hum Mol Genet. 2014 Aug 15;23(16):4315-27. doi: 10.1093/hmg/ddu148. Epub 2014 Apr 4. Hum Mol Genet. 2014. PMID: 24705357 Free PMC article.
775 results