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Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity.
Fan H, Xia S, Xiang J, Li Y, Ross MO, Lim SA, Yang F, Tu J, Xie L, Dougherty U, Zhang FQ, Zheng Z, Zhang R, Wu R, Dong L, Su R, Chen X, Althaus T, Riedell PA, Jonker PB, Muir A, Lesinski GB, Rafiq S, Dhodapkar MV, Stock W, Odenike O, Patel AA, Opferman J, Tsuji T, Matsuzaki J, Shah H, Faubert B, Elf SE, Layden B, Bissonnette BM, He YY, Kline J, Mao H, Odunsi K, Gao X, Chi H, He C, Chen J. Fan H, et al. Among authors: zhang r, zhang fq. Nature. 2023 Nov;623(7989):1034-1043. doi: 10.1038/s41586-023-06749-3. Epub 2023 Nov 22. Nature. 2023. PMID: 37993715 Free PMC article.
Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.
Chen D, Xia S, Zhang R, Li Y, Famulare CA, Fan H, Wu R, Wang M, Zhu AC, Elf SE, Su R, Dong L, Arellano M, Blum WG, Mao H, Lonial S, Stock W, Odenike O, Le Beau M, Boggon TJ, He C, Chen J, Gao X, Levine RL, Chen J. Chen D, et al. Among authors: zhang r. Mol Cell. 2021 Sep 16;81(18):3833-3847.e11. doi: 10.1016/j.molcel.2021.06.027. Epub 2021 Jul 20. Mol Cell. 2021. PMID: 34289383 Free PMC article.
Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation.
Gao X, Liu Y, Li Y, Fan H, Wu R, Zhang R, Faubert B, He YY, Bissonnette MB, Xia S, Chen D, Mao H, Boggon TJ, Chen J. Gao X, et al. Among authors: zhang r. Mol Cell. 2022 Jun 2;82(11):1992-2005.e9. doi: 10.1016/j.molcel.2022.03.026. Epub 2022 Apr 12. Mol Cell. 2022. PMID: 35417664 Free PMC article.
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